CRP联合SAA在小儿细菌性肺炎与支原体肺炎鉴别诊断中的应用价值

doi:10.3969/j.issn.1006-6233.2019.10.039

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Abstract Objective: To analyze the value of CRP combined with SAA in the differential diagnosis of bacterial pneumonia and mycoplasma pneumonia in children. Methods: :From December 2016 to December 2018, 100 cases of children hospitalized due to pulmonary infection in our hospital were selected and divided into two groups according to their infection status. Group a was a total of 75 cases of children with mycoplasma infection, while group b was a total of 25 cases of children with bacterial infection. Twenty healthy children who came to our hospital for physical examination in the same period were selected as the control group. The c-reactive protein level and serum amyloid A level of the three groups were determined and analyzed by ROC curve. Results: The CRP level and SAA level of children in the control group were significantly lower than those in group a and b, and the CRP level and SAA level of children in group a were significantly lower than those in group b (all P < 0.05). SAA/CRP ratios were not significantly different among the three groups (all P > 0.05). SAA test has a high diagnostic accuracy for children with bacterial infection and mycoplasma infection, while CRP test only has a high diagnostic accuracy for children with bacterial infection and has little significance for the differential diagnosis of children with mycoplasma infection. Conclusion: The detection of CRP and SAA has high accuracy in the diagnosis of bacterial infection in children, and the detection of SAA in the diagnosis and differential diagnosis of mycoplasma pneumoniae infection in children is also of high application value. It is worth popularizing and applying in clinic.

Key words： Mycoplasma pneumonia Bacterial pneumonia C-reactive protein Serum amyloid Differential diagnosis

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	DENG Wencheng
	WANG Wandang
	ZHANG Jieliang
	et al

Cite this article:

DENG Wencheng,WANG Wandang,ZHANG Jieliang, et al. Value of CRP combined with SAA in differential diagnosis of bacterial pneumonia and Mycoplasma pneumonia in Children[J]. HeBei Med, 2019, 25(10): 1737-1740.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2019.10.039 OR http://www.hbyxzzs.cn/EN/Y2019/V25/I10/1737

[1] RAM B, Dekkers T, Semmekrot BA, et al. Macrolide prescription in Dutch children: compliance with guidelines[J]. Eur Clin Microbiol Infect Dis, 2019,38(4):675~681.
[2] 袁玲,朱冠南,王红兵,等.阿奇霉素联合普米克令舒雾化吸入治疗小儿肺炎支原体感染的疗效及对免疫功能的影响[J].河北医学,2018,24(12):1969~1973.
[3] 田梅,陈启斌,李雪梅,等.C-反应蛋白、血清淀粉样蛋白A和YKL-40在小儿复发性肺炎中的联合检测作用[J].标记免疫分析与临床,2018,25(1):69~72,77.
[4] Shi W, Wei M, Wang Q, et al. Rapid diagnosis of Mycoplasma pneumonia infection by denaturation bubble-mediated strand exchange amplification: comparison with LAMP and real-time PCR[J]. Sci Rep, 2019,9(1):896.
[5] Thusang K, Onyearugbulem C, Chao J, et al. Case 4: altered mental status in a 6-year-old boy[J]. Pediatr Rev, 2019,40(2):88~89.
[6] 单平囡,叶利洪,甄国东,等.呼吸机相关性肺炎患者病原菌分布与C-反应蛋白及降钙素原水平的影响研究[J].中华医院感染学杂志,2016,(4):772~774.
[7] Hananeh WM, WMA M, Ababneh MM, et al. Mycoplasma bovis arthritis and pneumonia in calves in jordan: an emerging disease[J]. Vet World, 2018,11(12):1663~1668.
[8] 张华俐,王超,张蕊,等.内外合治法治疗小儿肺炎的疗效及其对降钙素原超敏C反应蛋白和免疫功能的影响[J].河北医学,2017,23(5):728~732.
[9] 季孝,刘思宇,史杨,等.PCT、CRP、SAA联合检测对儿童化脓性扁桃体炎的鉴别诊断价值[J].浙江医学,2018,40(12):1351~1354.
[10] Cai ZH, Dai YY, Huang LY, et al. Diagnosis of mycoplasma pneumoniae by loop-mediated isothermal amplification: systematic review and meta-analysis[J]. BMC Infect Dis, 2019,19(1):173.
[11] 徐磊.降钙素原、血清淀粉样蛋白A、肺表面活性蛋白和IL-6在重症肺炎的检测意义[J].标记免疫分析与临床,2017,24(8):911~913.