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| Comparative Analysis of Clinical Efficacy and Prognosis of Patients with Multiple Thyroid Nodules treated by Total Thyroidectomy and Subtotal Thyroidectomy |
| WANG Naijin, YING Haojie, SHI Jin, et al |
| Zibo Hospital in 960 Hospital of PLA, Shandong Zibo 255300, China |
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Abstract Objective:To explore the clinical efficacy and prognosis effects of patients with multiple thyroid nodules treated by total thyroidectomy and subtotal thyroidectomy. Methods:Ninety patients with multiple thyroid nodules in our hospital from March 2016 to August 2017 were retrospectively analyzed. They were divided into total thyroidectomy group (n = 45) and subtotal thyroidectomy group (n = 45). Total thyroidectomy group was treated by total thyroidectomy, and subtotal thyroidectomy group was treated by subtotal thyroidectomy. The clinical efficacy and prognosis of the two groups were compared. Results:The operative time and total hospital stay in total thyroidectomy group were longer than those in subtotal thyroidectomy group, and the length of incision was longer than that in subtotal thyroidectomy group, and the usage amount of analgesics was more than that in subtotal thyroidectomy group (P<0.05). The postoperative thyroid function indexes of free triiodothyronine (FT3) and free thyroxine (FT4) in total thyroidectomy group were lower than those in subtotal thyroidectomy group (P<0.05). There was no statistically significant difference in parathyroid gland function indexes between the two groups before and after surgery (P>0.05). The incidence rate of complications in total thyroidectomy group was higher than that in subtotal thyroidectomy group (17.78% vs 4.44%) (P<0.05). At 1 year after operation,the recurrence rate of total resection group was lower than that of subtotal resection group, and the difference was statistically significant (P<0.05). Conclusions:Subtotal thyroidectomy for patients with multiple thyroid nodules has less damage to their thyroid function and lower incidence of complications, while total thyroidectomy for patients with multiple thyroid nodules has lower recurrence rate. Both methods have their own advantages
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2019, Vol. 25 
