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| Effect of Plasmin on Deep Venous Thrombosis and its Effect on Venous Blood Flow Mechanics of Lower Extremity |
| FAN Huishuang, ZENG Hanqiang, MO Canjun, et al |
| Dongguan People's Hospital, Guangdong Dongguan 523059, China |
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Abstract Objective: To investigate the effect of plasmin on DVT and its effect on deep venous blood flow mechanics of lower limbs. Methods: Prospective selection of 184 DVT patients from June 2017 to February 2018 as subjects in our hospital. Divided into two groups according to the numerical random table method, 92 cases in each group. The control group was treated as a normal treatment, and the observation group was treated for plasmin. To observe the clinical efficacy of two patients. And compare the two groups before and after treatment in patients with hemodynamics and inflammatory reaction. Results: In clinical efficacy, the effective rate of the observation group was 92.39%, which was significantly higher than that of the control group (81.52%) (χ2= 4.792, P<0.05). There were no significant differences in FIB, PV, HSV and LSV between the two groups before treatment (P>0.05). After treatment, the FIB, HSV and LSV in the observation group were significantly lower than those in the control group (t=2.984,3.039,2.197,P<0.05). There were no significant differences in CRP, TNF- and il-6 between the two groups before treatment (P>0.05). After treatment, CRP, TNF-a and IL-6 in the observation group were significantly lower than those in the control group (t=9.999, 6.580, 8.536, P<0.05). Conclusion: Fibrinolytic therapy for DVT patients can improve clinical efficacy, significantly improve hemodynamics, and eliminate inflammatory factors.
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2019, Vol. 25 
