急性髂-股静脉血栓患者行临时下腔静脉放置联合滤器经患肢置管溶栓与经足背溶栓的治疗效果对比观察

doi:10.3969/j.issn.1006-6233.2018.03.017

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Abstract Objective: To investigate the therapeutic effect of temporary inferior vena cava in the treatment of thrombolytic and transposed thrombolysis in patients with acute iliofemoral vein thrombosis. Methods: From March 2012 to March 2016, 60 patients with acute iliac femoral vein thrombosis in our hospital were retrospectively analyzed. They were divided into catheter thrombolysis group (n=30) and dorsalis pedis thrombolysis group (n=30) according to the treatment. The clinical effects of the two treatment methods were compared after treatment, including the change of the circumference of the lower limbs, the rate of body swelling, the dosage of urokinase, the time of hospitalization, the rate of thrombolysis, the occurrence of thrombolysis, the long-term patency and the valvular function. Results: Catheter circumferential thrombolysis group before and after treatment, thigh and calf circumference difference and limb swelling rate were significantly higher than those in the dorsalis pedis thrombolysis group, the difference was statistically significant (P <0.05). The amount of urokinase and the time of hospitalization in the treatment of thrombolytic therapy were significantly lower than those in the back thrombolytic group (P <0.05). 2 weeks after treatment, the thrombolytic rate in the catheter thrombolysis group was significantly higher than that in the dorsalis pedis thrombolysis group, and the incidence of complications was significantly lower than that in the dorsalis pedis thrombolysis group. The above differences were statistically significant (P <0.05). Follow up for 18 months, venous catheterization rate in catheter thrombolysis group was significantly higher than that in the dorsalis pedis thrombolysis group, while the incidence of thrombotic syndrome (PTS) and thrombosis recurrence rate were significantly lower than those in the dorsalis pedis thrombolysis group, the difference was statistically significant (P <0.05). Conclusion: Thrombolytic therapy via small saphenous vein for patients with acute iliac femoral vein thrombosis has many advantages, such as good curative effect, short treatment time and low incidence of complications. It is worthy of further clinical application.

Key words： Acute iliofemoral deep vein thrombosis Urokinase Catheter-directed thrombolysis Vena cave filters Small saphenous vein

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	HUANG Yingjie
	LING Yongzhi
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HUANG Yingjie,LING Yongzhi,et al. Comparative Analysis of Small Saphenous Vein Thrombolysis by Infusion Catheter and Dorsalis Pedis Vein Directed Thrombolysis in Treatment for Central Venous Thrombosis after Temporary Inferior Vena Cava Filter[J]. HeBei Med, 2018, 24(3): 415-419.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2018.03.017 OR http://www.hbyxzzs.cn/EN/Y2018/V24/I3/415

[1] 李发旺,陈坤前,谢奎.经颈静脉放置临时滤器联合健侧股静脉穿刺置管治疗急性下肢深静脉血栓探讨[J].中外医疗,2016,35(32):84~86.
[2] Davies J,Tippet R,Watson A,et al.Systemic inflammatory response syndrome following catheter-directed thrombolysis of acute iliofemoral deep venous thrombosis[J].PhlebologyPhlebologyPhlebology,2016,32(1):61~65.
[3] Kohi MP,Kohlbrenner R,Kolli KP,et al.Catheter directed interventions for acute deep vein thrombosis[J].Cardiovasc Diagn Ther,2016,6(6):599~611.
[4] Ming Z,Li W,Yuan R,et al.Effectiveness of catheter directed thrombolysis and stent implantation on iliofemoral vein thrombosis caused by iliac vein compression[J].Thromb Thrombolysis,2017,44(2):254~260.
[5] Kuo T,Huang C,Hsu C,et al.Catheter-directed thrombolysis and pharmacomechanical thrombectomy improve midterm outcome in acute iliofemoral deep vein thrombosis[J].Journal of the Chinese Medical Association,2017,80(2):72~79.
[6] 王琦,孙思翘,程志华,等.急性髂股静脉血栓模型大鼠血清D-二聚体、纤维蛋白原、C反应蛋白、白介素6与血栓溶解体积之间的关联研究[J].中国实验血液学杂志,2016,24(5):1523~1528.
[7] 刘香芬.下肢深静脉联合腹部大血管彩超诊断深静脉血栓的价值探析[J].基层医学论坛,2016,20(24):3376~3377.
[8] Kwon SH,Ahn SE,Shin JS,et al.A phantom model study to identify the most effective manual aspiration thrombectomy for acute deep-vein thrombosis of the lower extremity[J].Clin Radiol,2016,71(4):321~327.
[9] 赵宇,朱兆红,秦金保,等.导管接触溶栓与机械辅助吸栓治疗急性髂股静脉血栓的对比研究[J].现代生物医学进展,2017,17(18):3486~3489.
[10] 尹孝亮,高涌,聂中林,等.腔内综合治疗髂股静脉血栓形成[J].中国普通外科杂志,2016,25(06):887~891.
[11] 景阳,丁萌,付久园,等.介入置管溶栓联合抗凝治疗产后合并下肢深静脉血栓的疗效分析[J].河北医学,2017,23(08):1316~1319.
[12] 陈千益,王华,胡晓曼,等.老年患者急性期下肢深静脉血栓形成导管接触性溶栓临床治疗[J].实用老年医学,2016,30(02):167~170.
[13] 吴云,梁川.机械吸栓、导管溶栓治疗急性髂股静脉血栓的临床体会[J].武汉大学学报(医学版),2017,38(01):138~141.
[14] 黄远清,杨福周,易远历,等.经小隐静脉置管导管溶栓治疗下肢深静脉血栓形成的应用研究[J].黑龙江医药,2016,29(06):1212~1214.
[15] 金良凤,陈敏.周围静脉与深静脉置管两种溶栓方法用于急性下肢深静脉血栓的疗效比较[J].武汉大学学报(医学版),2017,38(02):334~336