尼莫地平治疗蛛网膜下腔出血脑血管痉挛的有效性和安全性分析

doi:10.3969/j.issn.1006-6233.2018.03.014

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Abstract Objective: To investigate the efficacy and safety of nimodipine in the treatment of cerebral vasospasm caused by subarachnoid hemorrhage. Methods: 108 patients with SAH admitted to our hospital from January 2015 to January 2017 were randomly divided into two groups. Patients in the control group were given routine treatment, nimodipine plus nimodipine, The GCS score, Hunt-Hess grade, GOS score, BI index, disease-related parameters and adverse reactions were compared between the two groups. Results: The scores of GCS in the nimodipine group were significantly higher than those in the control group after treatment, and the scores of Hunt-Hess in the nimodipine group were lower than those in the control group. The GOS scores in the 3-month group were significantly lower than those in the control group (P <0.05). After treatment, the left TCD, the right TCD, the amount of hematoma, the levels of IL-6, SBP and DBP in the two groups were significantly lower than those in the control group There was no significant difference between the two groups in the incidence of adverse drug reactions and the overall incidence of treatment (P> 0.05). Conclusion: Nimodipine is effective in treating cerebral vasospasm of subarachnoid hemorrhage and has high safety.

Key words： Nimodipine Subarachnoid hemorrhage Cerebral vasospasm Adverse reactions

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2018.03.014 OR http://www.hbyxzzs.cn/EN/Y2018/V24/I3/405

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