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| The Clinical Research of Arotinolol for Treatment of Patients with Hypertension Associated with Anxiety and Depression |
| YANG Yang, LIU Yancheng, WANG Jing |
| The Central Hospital of Chengde, Hebei Chengde 067000, China |
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Abstract Objective: To investigate the clinical efficacy of Arotinolol treatment of patients with hypertension associated with anxiety and depression. Methods: 67 cases of patients with 1-2 stage hypertension associated with anxiety and depression disorder being evaluated by SAS and SDS from Chengde Central Hospital Hypertension clinic were divided into experimental group and control group from February 2016 to April 2017. The control group were treated with Enalapril 10mg once a day and the experimental group were treated with Arotinolol 10mg once a day for 4 weeks. Two groups were evaluated with Depression Rating Scale (SAS) and Self-Rating Anxiety Scale (SDS) and the blood pressure were measured before and after treatment. Results: The effects of hypertension in two groups showed significant difference (P < 0.01) than those before treatment. There was no significant difference in the level of blood pressure drops between the two groups (p> 0.05). The score of SAS and SDS were lower (P<0.01) in the experimental group showed significant difference (P<0.01) compared with the control group. The heart rate of the experimental group decreased significantly after treatment compared with that of the control group (p<0.01). Conclusion: Arotinolol can effectively reduce the blood pressure and score of Depression Rating Scale (SAS) and Self-Rating Anxiety Scale (SDS)。
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2018, Vol. 24 
