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Clinical Observation on the Treatment of Chronic Eczema with Dot Matrix Laser and Flumethasone |
LI Qingxian, ZHONG Shubin, ZHOU Wanyun |
The People's Hospital in Nanhai District of Foshan, Guangdong Foshan 528200, China |
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Abstract Objective: To investigate the clinical efficacy of dot-matrix laser combined with flumethasone in the treatment of chronic eczema. Methods: 100 patients with chronic eczema who were treated in outpatient department from July 2016 to September 2017 were randomly divided into two groups. Patients in the single drug group were treated with flumethasone, while patients in the combined group were treated with laser dextrose injection. VAS score was compared between the two groups , EASI score, overall treatment effect, cytokines and quality of life. Results:After treatment, the VAS score and EASI score in the combined group were significantly lower than those in the single drug group. The effective rate and total effective rate were significantly higher in the combination group than those in the single drug group. The levels of IL-2, IL-4, IL -10, IgE and LTB4 levels were significantly lower than the single drug group, IFN-γ levels were significantly higher than the single drug group; after treatment EPQOLS total score was significantly lower than the single drug group, there was a significant difference (P<0.05). Conclusion: The clinical efficacy of dot-matrix laser combined with flumethasone in the treatment of chronic eczema is significant and has reference value.
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