二氧化碳气腹对妇科子宫肌瘤腹腔镜手术患者术后早期认知功能的影响

doi:10.3969/j.issn.1006-6233.2017.09.001

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Abstract Objective: To investigate the effect of CO₂ pneumoperitoneum at different pressures on early postoperative cognitive function in patients undergoing laparoscopic surgery for uterine fibroids. Methods: 99 patients with uterine leiomyoma were enrolled from January 2015 to December 2015 were randomly divided into three groups. Group L was given low-pressure CO₂ pneumoperitoneum. The patients of group M were given an intermediate pressure level of CO₂ pneumoperitoneum. The patients of group H were given high pressure level of CO₂ pneumoperitoneum. The three groups of patients with clinical observation, neurochemical markers and cognitive function were compared. Results: T2 and T3 PaCO₂ levels and T1, T2 and T3 COR of group H were significantly higher than those in group L and group M|T2 and T3 PaCO₂ levels and T1, T2 and T3 COR of group M were significantly higher than those in group L|T5 PaO₂ level in patients with group H and group M was significantly lower than that in group L|T2, T3 and T4 NE the level was significantly higher than that of group L, T2, T1|T3 and T4 PGE2 were significantly higher than those in group L|group H of T1 patients with T2 NSE were significantly higher than those in group L and group M. S100β levels significantly higher than that in group L|T1 and T2 NSE of group M were significantly higher than those in group L, there was significant difference (P<0.05). Conclusion: Different air pressure pneumoperitoneum has little effect on the early cognitive function of patients with uterine leiomyoma after laparoscopic surgery, but low pressure CO₂ pneumoperitoneum can relieve the body stress and reduce the release of neurochemical markers.

Key words： CO₂ Uterine fibroids Laparoscopic surgery Cognitive function

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	MA Yulin
	LU Xinxing
	GONG Yongjuan
	et al

Cite this article:

MA Yulin,LU Xinxing,GONG Yongjuan, et al. Effect of CO₂ Pneumoperitoneum on Early Cognitive Function in Patients with Gynecological Uterine Leiomyoma after Laparoscopic Surgery[J]. 河北医学, 2017, 23(9): 1409-1411.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2017.09.001 OR http://www.hbyxzzs.cn/EN/Y2017/V23/I9/1409

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