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Effect of Pedicle Screw Fixation Combined with Posterolateral Bone Grafting and Fusion on Perioperative Indexes, JOA score, VAS score and Complications in Patients with Lumbar Spondylolisthesis |
WEI wei, LU Xianwei, HUANG Linhai, et al |
Guangxi Medical University, Guangxi Nanning 530199, China |
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Abstract Objective: To observe the effects of pedicle screw fixation combined with posterolateral lumbar fusion (PLF) on perioperative indexes, JOA score, VAS score and complications in patients with lumbar spondylolisthesis. Methods: A total of 90 patients with lumbar spondylolisthesis treated in the hospital from February 2013 to December 2016 were enrolled in the study. They were randomly divided into 2 groups with 30 patients in each group. Group A was treated with pedicle screw fixation combined with PLF, while group B was treated with pedicle screw fixation combined with intervertebral fusion. The spondylolisthesis rate, reduction rate, reduction loss rate and height loss rate were compared between the 2 groups at different time points. The JOA scores, VAS scores, therapeutic effects, operative indicators (intraoperative blood loss and operative time), postoperative bone graft fusion rate and complications in both groups were observed before treatment and at the end of follow-up. Results: The treatment was effective in both groups (P>0.05). There was no statistically significant difference in the operative time or intraoperative blood loss between the 2 groups (P>0.05). The bone graft fusion rate in group B was significantly higher than that in group A (P<0.05), but there was no significant difference in JOA score or VAS score between the two groups before operation and at the end of follow-up (P<0.05). JOA scores of both groups were significantly higher than while VAS scores were significantly lower than those before operation (P<0.05). The spondylolisthesis rate, height loss rate, reduction loss rate and the total incidence of complications in group A were significantly higher than those in group B during follow-up (P<0.05). Conclusion: Pedicle screw fixation combined with PLF or intervertebral fusion is effective in the treatment of lumbar spondylolisthesis. Compared with PLF, pedicle screw internal fixation combined with intervertebral fusion can maintain the correction of spondylolisthesis, with a advantage of reducing the risk of postoperative complications.
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