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| Effect of Traditional Chinese Medicine "Puren Dan" on Retinal Hemodynamics in Diabetic Retinopathy |
| WANG Haibin, FENG Peiming, DONG Zhijun, et al |
| The Affiliated Hospital of Chengde Medical College, Hebei Chengde 067000, China |
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Abstract Objective: To observe the effect of traditional Chinese medicine "Purendan" on retinal hemodynamics in patients with simple diabetic retinopathy. Methods: The peak systolic velocity (Vs), end diastolic velocity (Vd), and obstruction of central retinal artery (CRA) and central retinal vein (CRV) were measured by color Doppler flow imaging (CDFI) in 20 normal subjects. Force index (RI) was measured by fundus fluorescence angiography (FFA) in 20 patients with diabetes mellitus. Patients with stage I and stage II diabetic retinopathy were treated with Borendan for 6 months. The central retinal artery was performed by color Doppler flow imaging (CDFI) before and after treatment. The peak systolic velocity (Vs), end diastolic velocity (Vd) and resistance index (RI) of CRA and CRV were measured. Results: Before treatment, the blood flow velocity of central retinal artery and central retinal vein in diabetic patients was significantly lower than that of normal people, and the resistance index was higher than that of normal people (P<0.05). After treatment, the parameters of central retinal artery blood flow basically returned to normal, and the velocity of central retinal vein blood flow was significantly improved, but still lower than normal. The resistance index of central retinal artery and central vein changed significantly before and after treatment (P<0.05). Conclusion: Retinal hemodynamics of diabetic retinopathy patients treated with traditional Chinese medicine Bo Ren Dan has been significantly improved, thus confirming the effectiveness of traditional Chinese medicine Bo Ren Dan on DR treatment.
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2018, Vol. 24 
