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| The Clinical Effect of Total Endoscopic Surgery and Traditional Surgical Treatment for Early Differentiated Thyroid Adenocarcinoma |
| QIU Hongbo, TANG Le, DOU Gang, et al |
| The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Xi'an 710061, China |
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Abstract Objective: To compare the clinical effect of total endoscopic surgery and traditional surgical treatment for early differentiated thyroid adenocarcinoma. Methods: 92 cases of early differentiated thyroid adenocarcinoma treated in our hospital from January 2014 to June 2017 were retrospectively analyzed. According to different treatment methods, they were divided into control group (n=48) and study group (n=44). The control group was treated with traditional surgery, and the study group was treated with total endoscopic surgery. The operation condition, stress reaction, complications, cosmetic effect and follow-up of the two groups were compared. Results: Operation time, postoperative 24 hours flow rate in research group were more than the control group, incision length, intraoperative blood loss, postoperative 24 hours VAS and length of hospital stay were lower than the control group, there was statistically significant differences (P<0.05), central lymph node dissection between two group was no difference (P>0.05). 12h, 24h after surgery, the CD4+, CD4+/CD8+ in both group were lower, the research group were higher than the control group, CD8+, c-reactive protein (CRP) and interleukin-6 (IL-6) and tumor necrosis factor-α(TNF-α) in both group were rised, the research group were lower than the control group, there was a statistically significant difference between the two groups in postoperative 12h and 24h (P<0.05). Total complication rate in both group was no statistical difference (P>0 0.05). The total satisfaction of research group was higher than that of the control group (P<0.05). during the follow-up, there was no tumor recurrence and metastasis in both groups, and there was no statistical difference (P>0.05). Conclusion: Long-term efficacy of total endoscopic surgery in the treatment of early differentiated thyroid adenocarcinoma is similar with traditional surgical treatment, however, full-endoscopic surgery has advantages, such as beauty and minimally invasive surgery, it's a better technique for patients with this indication.
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2018, Vol. 24 
