后腹腔镜肾囊肿去顶减压术后患者应激相关指标水平变化及临床意义分析

doi:10.3969/j.issn.1006-6233.2019.02.035

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Abstract Objective: To analyze the changes in the level of stress-related markers in patients undergoing decompression of a new retroperitoneal renal cyst and its clinical significance. Methods: 120 patients with renal cysts who were examined in our hospital from July 2014 to March 2018 were randomly divided into study group and control group, each with 60 cases. The patients in the study group underwent single-hole laparoscopic resection of renal cysts and decompression. The patients in the control group underwent conventional retroperitoneoscopic renal cyst decompression. The clinical efficacy, body temperature, blood pressure, and blood glucose levels, cortisol, thyroid stimulating hormone (TSH), total triiodothyronine (TT3), and blood were compared before and after surgery on the 1st, 2nd, and 3rd days in the two groups of renal cyst patients. Total tetraiodothyronine (TT4) content, WBC and CRP levels, IL-6 and IL-8 levels, IgG, IgA and IgM levels, andCD4⁺,CD8⁺and CD4⁺/CD8⁺ ratios. Results: There was no significant difference in the operation time, length of stay, and blood loss between the study group and the control group. There was no significant difference between the two groups (P>0.05). The incidence of postoperative complications in study group and control group were 5.00% and 13.33%, respectively, and the difference between control group and study group was statistically significant (P<0.05); the study group and control group were postoperative There were significant differences in preoperative and postoperative blood glucose levels between 1st, 2d, and 3d (P<0.05). There was no significant difference in SBP and DBP between the two groups (P>0.05). There was a significant difference in the TT3 between the study group and the preoperative patients on the first postoperative day (P<0.05), but there was no statistically significant difference in the TSH, TT3, and TT4 levels between the two groups compared with the preoperative ones (P>0.05); The levels of CRP, IL-6 and IL-8 in the control group at the 1st, 2nd, and 3rd postoperative days were significantly different from those in the study group (P<0.05); There was no significant difference in the levels of IgG, IgA and IgM between the 2nd and 3rd day after operation (P>0.05). There was no significant difference in the levels of CD4 +, CD8 + and CD4 +/CD8⁺between the two groups on the 2nd and 3rd postoperative days (P>0.05). Conclusion: After retrograde decompression of a new type of retroperitoneal renal cyst, the changes in body temperature, blood pressure, blood glucose, WBC and CRP levels are smaller, and they have little impact on the patient's immune function, rapid recovery, and less trauma.

Key words： Retroperitoneoscopic renal cyst decompression Single hole Renal cyst Stress response

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2019.02.035 OR http://www.hbyxzzs.cn/EN/Y2019/V25/I2/307

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