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| Diagnosis Value of Serum β-HCG ALP Combined Transabdominal Color Doppler Ultrasound for Early Ectopic Pregnancy |
| LIU Aihua, WANG Dong, YAO Shuiping, et al |
| Hengshui People's Hospital / Halixun International Peace Hospital, Hebei Hengshui 053000, China |
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Abstract Objective: To investigate the value of serum β-human chorionic gonadotropin (β-HCG), alkaline phosphatase (ALP) and transabdominal color doppler ultrasound in the diagnosis of ectopic pregnancy. Methods: A total of 47 patients with ectopic pregnancy in our hospital from March 2017 to March 2018 were selected. 51 pregnant women with normal pregnancy were selected as controls. Retrospective analysis of serum β-HCG, ALP level and the gestational sac, endometrial thickness and other indicators detected by transabdominal color Doppler ultrasound and compared. Results: The incidence of abdominal pain, vaginal bleeding, abdominal tenderness, uterine enlargement, attachment tenderness and cervical lift were significantly higher in ectopic pregnancy group than that in normal pregnancy group (P<0.05). The level of serum β-HCG in ectopic pregnancy group was significantly lower than that in normal pregnancy group [(1554.12±279.21) vs (3267.98±610.21) mIU/mL, P<0.05]. The level of serum ALP in ectopic pregnancy group was significantly lower than those in the normal pregnancy group [(29.45±5.23) vs (42.37±9.72) mIU/mL, P<0.05]. Spearman test showed that serum β-HCG level was positively correlated with ALP level in ectopic pregnancy group (r = 0.630, P<0.05). The incidence of endometrial thickness ≤ 10mm, attachment area with mass, intrauterine no gestational sac, fetal heart rate in ectopic pregnancy group was significantly higher than that of the normal pregnancy group (P<0.05). The of serum β-HCG and ALP in combination with abdominal color Doppler ultrasonography were 96.08%, which were higher than those used one of them (P<0.05). Conclusion: Combined serum β-HCG, ALP with abdominal color Doppler ultrasonography can significantly improve the diagnosis rate of early ectopic pregnancy, which is valuable to promote.
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2019, Vol. 25 
