生长抑素治疗腹部手术后腹腔感染的疗效及对血清AMS的影响

doi:10.3969/j.issn.1006-6233.2019.01.016

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Abstract Objective: To study effect of somatostatin on abdominal infection after abdominal operation and its influence on serum amylase. Methods: 79 abdominal operations who received therapy from March 2013 to February 2018 in our hospital were selected as research objects. According to simple random number table, those patients were divided into the observation group (n=37) and the control group (n=42). The control group was treated with conventional therapy, while the observation group was on the basis of the control group, somatostatin was used. Then the therapeutic effect, disappearance time of clinical symptoms (nausea and vomiting, abdominal distension and abdominal pain, anal exhaust time), hospitalization time, serum AMS, ascites AMS level, incidence of adverse reactions of two groups after treatment were compared. Results: After treatment, the total effective rate of observation group was statistically higher than that in the control group [94.59% (35/37)vs 66.66%(28/42)](P<0.05); The time of disappearance of clinical symptoms and the time of hospitalization were lower than those of the control group [(1.89±0.70)d vs(4.01±1.21)d, (2.90±0.58)d vs(6.27±1.34)d, (3.76±0.82)d vs (5.80±1.35)d,(4.59±1.02)d vs(7.40±2.15)d](P<0.05); The levels of serum AMS and ascites AMS were significantly lower than those in control group [(142.01±19.42)U/L vs(297.46±26.04)U/L,(124.21±18.47)U/L vs(305.98±31.27)U/L](P<0.05); The total incidence of adverse reactions was lower than that of the control group [8.10%(3/37) vs 28.57%(12/42)](P<0.05). Conclusion: Somatostatin is effective in the treatment of abdominal infection after abdominal surgery. It can effectively improve clinical symptoms, promote postoperative recovery, reduce adverse reactions, and reduce serum AMS. It is safe and reliable.

Key words： Somatostatin Abdominal infection Amylase

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	YANG Zhigang

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YANG Zhigang. Effect of Somatostatin on Abdominal Infection after Abdominal Surgery and its Influence on Serum AMS[J]. HeBei Med, 2019, 25(1): 63-65.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2019.01.016 OR http://www.hbyxzzs.cn/EN/Y2019/V25/I1/63

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