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Value of CTA in Evaluating Cerebrovascular Stenosis in Patients with Ischemic Stroke |
WU Jing, et al |
Nanjing First Hospital, Nanjing Medical University, Jiangsu Nanjing 210001, China |
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Abstract Objective: To observe the value of CT angiography (CTA) in evaluating the degree of cerebrovascular stenosis in patients with ischemic stroke (IS). Methods: The clinical data of 110 patients with IS admitted to the hospital from January 2020 to June 2023 were analyzed retrospectively. All patients were examined with conventional transcranial Doppler ultrasound and CTA. Digital subtraction angiography (DSA) was taken as the golden standard to compare the value of Doppler ultrasound and CTA in evaluating the degree of cerebrovascular stenosis in patients with IS. Results: DSA found 24 cases of mild cerebrovascular stenosis, 63 cases of moderate stenosis, 13 cases of severe stenosis, and 10 cases of occlusion. Among them, the proportion of extracranial arteries (56.36%) is higher than that of intracranial arteries (43.64%). The sensitivity, specificity and accuracy of Doppler ultrasound in evaluating moderate or more severe cerebrovascular stenosis in patients with IS were 54.17%, 77.91% and 72.73%. The sensitivity, specificity and accuracy of CTA were 95.83%, 88.37% and 90.00%. The sensitivity, accuracy, positive predictive value and negative predictive value of CTA in evaluating moderate or more severe cerebrovascular stenosis in patients with IS were significantly higher than those of Doppler ultrasound (P<0.05). There was no significant difference in specificity between the two methods (P>0.05). Conclusion: CTA is of high value in evaluating the degree of cerebrovascular stenosis in patients with IS, and its sensitivity and accuracy are higher than those of conventional Doppler ultrasound. It can clearly show the patients' cerebrovascular lesions, providing reference for clinical diagnosis and treatment.
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