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Analysis of the Effect of Calcium Hydroxide Combined with Chlorhexidine on the Pain Level and Disinfection Effect of Root Canal Disinfection in Patients |
YU Xuefei, WANG Nana, WANG Qiongqiong, et al |
Fuyang People's Hospital, Anhui Fuyang 236000, China |
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Abstract Objective: To compare the influence of calcium hydroxide combined with chlorhexidine and calcium hydroxide alone on the disinfection effect and postoperative pain degree in patients with root canal disinfection, and to explore the clinical application effects of different drugs. Methods: A total of 102 patients with root canal disinfection who were treated in the hospital from Jun. 2019 Dec. 2022 were selected as the research subjects, and were simply randomized into combined group (n=51) and conventional group (n=51) by using the random number table method. The conventional group adopted calcium hydroxide alone for root canal disinfection, while the combined group received calcium hydroxide combined with chlorhexidine for root canal disinfection. At 7 days after medicine sealing, the disinfection effect, Mohdsulong pain grading, and incidence rates of complications were compared between the two groups. The colony counts of aerobic bacteria and anaerobic bacteria in root canal before and after root canal preparation and at 7 days after medicine sealing and the sealing time of the two groups of patients were compared. Results: The effective rate of disinfection of the combined group was 98.04%, which was higher than 80.39% of the conventional group (P<0.05). There were no statistical differences in the counts of aerobic and anaerobic bacteria between the two groups before and after root canal preparation (P>0.05). At 7 days after medicine sealing, the counts of aerobic bacteria and anaerobic bacteria in the root canal of the combined group were less than those of the conventional group (P<0.05). The pain grading of the combined group was better compared with that of the conventional group (P<0.05), and the sealing time was shorter than that in the conventional group (P<0.05). The incidence rate of gingival swelling and total incidence rate of complications were lower in the combined group than those in the conventional group (P<0.05). Conclusion: Compared with calcium hydroxide alone, the application of calcium hydroxide combined with chlorhexidine for root canal disinfection can achieve better disinfection effect, and can more effectively inhibit the bacterial reproduction, relieve the pain of root canal treatment, and shorten the root canal treatment time, with higher safety.
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