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| Analysis of the Relationship between Neutrophil/Lymphocyte Ratio and CAD in Postmenopausal Women |
| ZHAO Lixia, GAO Yuan, WANG Rui, et al |
| Chengde Central Hospital, Hebei Chengde 067000, China |
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Abstract Objective: To investigate the relationship between neutrophil/lymphocyte ratio (NLR) in blood and CAD in postmenopausal women, and to provide a strong basis for clinical treatment of coronary artery lesions in postmenopausal women with CAD. Methods: A total of 260 postmenopausal female CAD patients diagnosed by coronary angiography (CAG) in our hospital from June 2020 to June 2021 were selected as the case group. At the same time, 260 women with suspected CAD during the same period, but whose CAD was ruled out by clinicians and ancillary tests, were selected as a control group. A retrospective analysis was conducted. Results: There was no significant difference in BMI, age at menopause and family history of CAD between the two groups of patients (P>0.05). Patients in the study group with older age, longer menopause, and combined hypertension and diabetes mellitus were statistically analyzed (P<0.05). It can be seen from the laboratory indicators that the white blood cells, NLR, TG and aspartate aminotransferase of the case group were significantly higher than those of the control group, with statistical differences (P<0.05); PCT, HDL, fibrin, and ApoA were significantly lower than those of the control group, there was a statistical difference (P<0.05). There were 119 cases in the severe group, 72 cases in the moderate group, and 69 cases in the mild group of CAD patients. Statistical multi-group comparison was performed by ANOVA, F=3.538, P<0.05, the difference was statistically significant. The difference was not statistically significant (P>0.05) when comparing the mild group with the moderate group by the LSD method between two groups, and the difference was statistically significant (P<0.05) when comparing the mild group with the severe group and the moderate group with the severe group. Logistic regression equation showed that age, hypertension, NLR, TG and fibrin were independent risk factors for coronary heart disease (CAD) in postmenopausal women. Conclusion: The NLR is a convenient and inexpensive blood test that allows clinicians to identify high-risk patients early and can effectively assess and predict the severity of CAD coronary arteries in postmenopausal women.
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2023, Vol. 29 
