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| Analysis of the Relationship Between PE and Pregnancy Outcome in Advnanced Pregnant Women and the Effect of Calcium Combined with Aspirin on the Prevention of PE |
| ZHANG Xiaofeng, LIU Xiaojing, JIA Xiufeng, et al |
| Department of Obstetrics and Gynecology, Ningde Hospital, Fujia Ningde 352100,China |
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Abstract Objective: To explore the relationship between preeclampsia (PE) and pregnancy outcome in advanced pregnant women and to analyze the preventive effect of calcium combined with aspirin on PE. Methods: A retrospective analysis was conducted of the clinical data of 169 advanced pregnant women who underwent obstetrics and delivery from March 2019 to December 2020 in the Department of Obstetrics and Gynecology of our hospital, and the subjects were divided into PE group (68 cases) and non-PE group (101 cases) according to whether PE developped. The 68 patients in the PE group were divided into the intervention group (37 patients) and the non-intervention group (31 patients) according to whether they had calcium combined with aspirin intervention or not. The differences in singleton live births, gestational weeks of delivery and neonatal weight between the PE and non-PE groups were compared, as well as the pregnancy outcomes of the different groups. Results: Gestational weeks of delivery and neonatal weight were significantly lower in the PE group than in the non-PE group, P<0.05. The incidence of preterm delivery, fetal distress and fetal growth restriction in the PE group was higher than that in the non-PE group, P<0.05. The incidence of preterm delivery, fetal distress, fetal growth restriction in the non-intervention group was higher than that in the intervention group, P<0.05. Conclusion: PE has significant adverse effects on pregnancy outcome in advanced pregnant women. The combination of oral calcium and low-dose aspirin in advanced pregnant women with PE can effectively improve pregnancy outcomes, reduce the incidence of preterm births and stillbirths, improve the quality of newborn births, and achieve a more desirable maternal and infant outcome.
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2022, Vol. 28 
