分化型甲状腺癌患者术后放射性131碘的清甲疗效及影响因素

doi:10.3969/j.issn.1006-6233.2022.05.025

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Abstract Objective: To explore thyroid ablation efficacy and influencing factors of postoperative radioactive 131 iodine (¹³¹I) in patients with differentiated thyroid carcinoma (DTC). Methods: 86 patients with thyroid cancer treated in our hospital from January 2019 to March 2020 were selected and divided into successful and unsuccessful ablation efficacy groups according to the effect of ablation efficacy. The differences of gender, age, pathological type, body mass index, TSH level and STG level before ¹³¹I first treatment, primary risk stratification, primary lesion diameter, TNM stage, metastasis and ¹³¹I first treatment dose between the two groups were analyzed by single factor statistics, Multivariate logistic regression was used to analyze the influencing factors of ¹³¹I nail cleaning efficacy in patients with DTC. Results: Among the 86 patients with DTC, 52 cases had successful ablation efficacy, and the successful rate was 60.47%. Univariate analysis showed that there were significant differences in STG level, recurrence risk stratification, primary lesion diameter and ¹³¹I first treatment dose between the successful group and the unsuccessful group (P<0.05); There was no significant difference in gender, age, pathological type, body mass index, TSH level, TNM stage and lymph node metastasis before ¹³¹I treatment (P>0.05). Multivariate logistic regression analysis showed that the level of STG before the first treatment of ¹³¹I, the diameter of primary lesion and the first treatment dose of ¹³¹I were the independent influencing factors of ¹³¹I ablation efficacy in patients with DTC (P<0.05). Conclusion: The success rate of thyroid ablation is 60.47% in the 86 patients with DTC. The sTg level before the first ¹³¹I treatment, diameter of primary lesions and dosage of the first ¹³¹I treatment are independent influencing factors of thyroid ablation efficacy of ¹³¹I on DTC patients.

Key words： Differentiated thyroid carcinoma Radioactive 131 iodine Thyroid ablation efficacy Influencing factor

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2022.05.025 OR http://www.hbyxzzs.cn/EN/Y2022/V28/I5/818

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