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| Effect of Local Application of Bone Wax and Tranexamic Acid on Postoperative Bleeding and Short-Term Knee Function during Unicondylar Arthroplasty |
| SUN Shaosong, LU Wenhai, SHI Sifeng |
| The Affiliated Hospital of Xuzhou Medical University, Jiangsu Xuzhou 221000, China |
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Abstract Objective: The effect of bone wax and tranexamic acid on postoperative bleeding and short-term knee function during unicondylar arthroplasty was analyzed. Methods: A total of 84 patients who underwent unicondylar joint replacement in our hospital from April 2020 to October 2021 were selected as the research subjects. The patients were divided into 4 groups by lottery technique with simple random method, with 21 cases in each group. Group A received compression dressing, group B received bone wax, group C received tranexamic acid, and group D received bone wax combined tranexamic acid. The amount of blood loss, hemoglobin and coagulation function before and 1 week after operation, and knee function before and 1 week and 1 month after operation were compared in 4 groups. Results: The intraoperative blood loss, postoperative blood loss and perioperative total blood loss in groups B, C and D were lower than those in group A (P<0. 05), while the blood loss in groups C and D was lower than that in group B (P<0. 05), and there was no statistical significance between group C and group D (P>0. 05). One week after operation, hemoglobin (HB) and fibrinogen (FIB) in groups B, C and D were higher than those in group A (P<0. 05), and those in groups C and D were higher than those in group B (P<0. 05), but there was no statistical significance between group C and group D (P>0. 05). 1 week and 1 month after surgery, there was no significant difference in HSS scores of knee joints among the 4 groups (P>0. 05). Conclusion: Topical application of bone wax or tranexamic acid in monondylar joint replacement can reduce the amount of blood loss in patients, but tranexamic acid and bone wax combined with tranexamic acid has better hemostatic effect than bone wax alone, and does not affect the recovery of knee function.
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2022, Vol. 28 
