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The Predictive Value of CK AFP and β-hCG in Maternal Serum for Placental Implantation |
QIU Xiaoru, LIU Xiaohua, WU Xinxin, et al |
Chengde Central Hospital, Hebei Chengde 067000, China |
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Abstract Objective: Based on the levels of CK, AFP and β-hCG in the maternal serum, the value of predicting placenta accreta was explored. Methods: 50 cases of puerpera in the obstetrics department of Chengde Central Hospital from 2017 to 2019 who were pathologically diagnosed as placenta accreta were selected as the experimental group. 52 cases of non-placental implant women were randomly selected as the control group. The maternal serum CK, AFP and β-hCG levels were measured in each group, and the datas were analyzed by spss23.0 statistical software. Results: The levels of the three types of indicators in the experimental group were significantly higher than those in the control group. The datas were compared and the differences were statistically significant; and the three types of indicators had a certain predictive value for placental accreta, and the combination of the three indicators has higher predictive value for placenta accreta, with sensitivity and specificity of 70% and 81% respectively.The cut off values of serum CK, AFP and β-hCG for placenta accreta is 153.14U/mL, 193.23U/mL and 21909U/L. Conclusion: The combination of CK,AFP and β-hCG in maternal serum can effectively predict the placental accreta of pregnant women before delivery, and the predictive value is relatively high.
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[1] 谢幸,孔北华,段涛等.妇产科学[M].第9版.北京:人民卫生出版社,2018.153. [2] Sebastian R, Hobson, JohnC,et al.Screening,diagnosis,and management of placenta accreta spectrum disorders.[J]. Obstet Gynaecol Can,2019,41(7):1035~1049. [3] 高翠萍.彩色多普勒血流显像联合血清甲胎蛋白、肌酸激酶检测在孕晚期孕妇产前胎盘植入诊断中的应用[J].实用医药影响杂志,2018,19(1):70~71. [4] 秦燕明,王鹏,李政,等.多发伤患者血清中肌红蛋白、肌酸激酶和相关炎性介质的表达及临床意义[J].中国呼吸及危重监护杂志,2017,16(1):50~54. [5] Fukumitsu K,Fujishima K,Yoshimura A,et al.Synergistic action of dendritic mitochondria and creatine kinase maintains atp homeostasis and actin dynamics in growing neuronal dendrites [J].Neurosci,2015,35(14):5707~5723. [6] 金日男,许红雁,钟永红,等.血清甲胎蛋白联合彩色超声检查在胎盘植入产前诊断中的价值[J].现代妇产科进展,2016,25(8):611~613. [7] 张丽,赵春明,王琳,郭金宝,尹博宇,刘亭亭.胎盘植入程度及类型的产前诊断研究进展[J].大连医科大学学报,2020,42(05):448~453. [8] 彭海燕.多普勒超声甲胎蛋白与人绒毛膜促性腺激素对前置胎盘胎盘植入预测作用分析[J].山西医药杂志,2017,46,(6):638~640. |
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