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| The Diagnostic Value of PET-CT SUV for Postoperative Recurrence and Metastasis of Colorectal Cancer |
| ZHANG Jiang, CHEN Yaming, WANG Meng, et al |
| The General Hospital of Wanbei Coal Power Group, Anhui Suzhou 234000, China |
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Abstract Objective: To explore the changes in the standard uptake value (SUV) of positron emission computed tomography (PET-CT) in patients with colorectal cancer before surgery, and to analyze the diagnostic predictive value of PET-CT SUV for postoperative recurrence and metastasis of colorectal cancer. Methods: A total of 50 patients with colorectal cancer, from November 2017 to August 2020, who met the inclusion criteria in this study were included as observation subjects for retrospective study. The 50 patients underwent whole-body PET-CT examination before surgery, and the highest SUV (SUVmax) in the specific area of colorectal cancer lesions was calculated. In the follow-up the correlation between SUVmax and recurrence or metastasis was observed, and the diagnostic efficacy of SUVmax for colorectal cancer recurrence and metastasis was analyzed. Results: The median follow-up time was 23.5 months, and the follow-up rate was 100%. Of the 50 patients, 24 had local recurrence or metastasis, and 26 patients had no recurrence or metastasis. The preoperative SUVmax of patients with local recurrence or metastasis after operation was (5.3±2.3), and the preoperative SUVmax of patients without recurrence and metastasis after operation was (2.7±0.6). The preoperative SUVmax of the former was significantly higher than the latter, and the difference was statistically significant (t=4.587, P<0.05).When preoperative SUVmax=4.2, the diagnostic sensitivity and specificity of colorectal cancer recurrence and metastasis were 72.0% and 100.0% respectively, and the negative and positive predictive values were 73.0% and 100.0% respectively. Conclusion: The higher the preoperative SUVmax of colorectal cancer patients, the greater the chance of tumor recurrence and metastasis in the near future. The preoperative SUV has important value in predicting the recurrence and metastasis of colorectal cancer patients.
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2021, Vol. 27 
