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| Effect of Ropivacaine and Sufentanil Combined Spinal-Epidural Anesthesia for Cesarean Section on Hemodynamics and Muscle Relaxation |
| DENG Guokui, LI Yunxian, XIE Hong, et al |
| Hefei Tumor Hospital, Chinese Academy of Sciences, Anhui Hefei 230000, China |
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Abstract Objective: To explore the effect of ropivacaine and sufentanil combined spinal-epidural anesthesia for cesarean section on hemodynamics and muscle relaxation. Methods: A prospective selection of 80 parturients who underwent cesarean section in our hospital from January 2019 to June 2020 were randomly divided into two groups according to the random number table method. The control group (40 cases) had ropivacaine combined spinal-epidural anesthesia, and the observation group (40 cases) had ropivacaine combined with sufentanil combined spinal-epidural anesthesia. The changes in heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) levels 15 minutes before anesthesia and 15 minutes after anesthesia between the two groups of women were compared, as well as the degree of muscle relaxation after anesthesia, drug onset time, analgesia time, exercise recovery time, and maternal Bromage exercise score, Apgar score of newborns 15 minutes postpartum, and occurrence of adverse drug reactions. Results: Repeated measurement analysis of variance showed that the time point effect can significantly affect the changes in SBP, DBP and HR levels, and the interaction effect of time point and anesthesia methods can significantly affect the changes in SBP levels (P<0.05); and the decrease in SBP in the observation group after anesthesia was lower than that in the control group (all P<0.05). The excellent and good rate of muscle relaxation in the observation group was 97.50%, which was higher than 85.00% in the control group. The difference was statistically significant (P<0.05). Compared with the control group, the observation group had no statistically significant differences in the time of drug onset, Apgar score of the newborn, Bromage exercise score, analgesia time and exercise recovery time(P>0.05). Conclusion: Ropivacaine and sufentanil combined spinal-epidural anesthesia for cesarean section has little effect on hemodynamics, high rate of muscle relaxation, and does not affect the function of the lower limbs of the mother and the health of the newborn. The drug has high safety.
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2021, Vol. 27 
