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| Epidemiological Characteristics and Clinical Analysis of 191 Cases of Childhood Measles Complicated with Severe Pneumonia |
| SUN Ling, CUI Xiaowei, SUN Yishuo, et al |
| Hebei Children's Hospital, Hebei Shijiazhuang 050031, China |
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Abstract Objective: To analyze the epidemiological and clinical characteristics, treatment measures and prognosis of children with measles complicated with severe pneumonia, so as to provide evidence for measles prevention and control and reduce the mortality of severe measles. Methods: From 2011 to 2019, 191 children with measles and severe pneumonia admitted to the inpatient ward of Hebei Children's Hospital were made the research object. The clinical data of the children were retrospectively studied, and the epidemiological characteristics were analyzed by descriptive epidemiology. At the same time, the clinical features, treatment and prognosis of children were also analyzed. Results: The male to female ratio of 191 cases was 1.93:1. The onset time was from January through June, and the age was mainly under 1.5, accounting for 90.06%. The regional distribution was mainly in the surrounding cities and rural areas, accounting for 88.48%; 69 cases ( 36.12%) have a previous medical history, all children have symptoms such as fever, rash, cough, shortness of breath, and three concave signs. The most common complication is laryngitis in 129 cases (67.54%), white blood cells, CRP, myocardial enzymes, liver function, blood sugar, and imaging examinations all had different degrees of abnormality. The sputum culture was mainly Escherichia coli; after comprehensive assessment and targeted treatment, 107 cases (56.02%) were cured and discharged, and 74 cases (38.74%) were improved and discharged. 10 cases died or died after giving up treatment. Conclusion: The overall incidence of measles complicated with severe pneumonia fluctuated significantly from 2011 to 2019, and 2014 was the peak of the incidence. The respiratory, digestive, and cardiovascular systems of the children could be affected. The causes of death were respiratory failure, ARDS, and MODS. The coverage rate and timely vaccination rate of children with measles component vaccine (MCV) should be treated in a timely manner based on clinical manifestations of severely ill children to reduce the mortality rate and improve the prognosis of children.
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2021, Vol. 27 
