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| Predictive Value of Serum CRP PCT Levels and ISS in Severe Multiple Trauma Patients with Abdominal Injury |
| MA Wujian, LI Yucui |
| The Affiliated Hospital of Jining Medical College, Shandong Jining 272000, China |
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Abstract Objective: To analyze the diagnostic value of serum C-reactive protein (CRP), procalcitonin (PCT) and injury severity score (ISS) in patients with severe multiple trauma and abdominal injury, and the prediction of death of patients with organ injury. Methods: The clinical data of 93 patients with severe multiple trauma with abdominal injury in our hospital from August 2017 to January 2020 were retrospectively analyzed. According to the presence or absence of organ injury, the patients were divided into group A (48 cases without organ injury) and group B (45 cases with organ injury). The serum CRP, PCT levels and ISS score were analyzed, and the receiver operating characteristic curve (ROC) was used to analyze the diagnostic value of CRP, PCT and ISS scores in organ injury and to predict death of patients with organ injury. Results: Comparison of PCT, CRP and ISS scores between groups A and B showed statistically significant differences (P<0.05). According to the ROC analysis results, the AUC of PCT, CRP and ISS scores for predicting the death of organ injuries were 0.743, 0.808, and 0.800 respectively; according to the best cut-off value: PCT has a sensitivity of 55.6% and specificity is 97.7%; CRP has a sensitivity of 71.1% and specificity of 83.3%; ISS points have a sensitivity of 60.0% and specificity of 89.6%. In group B, 15 patients with organ injury survived and 30 died. The PCT, CRP and ISS scores of the two types of patients were compared, and the difference was statistically significant (P<0.05). According to the ROC analysis results, the AUC of PCT, CRP and ISS scores for predicting the death of organ injuries were 0.977, 0.976, and 0.960, respectively. According to the best cut-off value: PCT has a sensitivity of 97.0% and a specificity of 86.7%; CRP has a sensitivity of 96.7 and specificity of 86.7%; ISS points have a sensitivity of 98.2% and specificity of 80.0%. Conclusion: If there is organ damage in patients with severe multiple injury and abdominal injury, their PCT, CRP levels and ISS score will be significantly increased, and have certain value in the diagnosis of organ damage, but PCT, CRP levels and ISS have higher value in predicting patients' death.
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2021, Vol. 27 
