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| Diagnostic Value of MRI and DCE-MRI in Ovarian Tumors and Tumor Like Lesions |
| LU Longlong, WANG Dong, LIAN Peng, et al |
| Xi'an People's Hospital/Xi'an Fourth Hospital, Shaanxi Xi'an 710004, China |
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Abstract Objective: To explore the diagnostic value of magnetic resonance imaging (MRI) and dynamic contrast-enhanced MRI (DCE-MRI) in ovarian tumors and tumor-like lesions. Methods: 81 patients with ovarian tumors (ovarian tumor group) and 132 patients with tumor-like lesions confirmed by surgical pathology (tumor-like lesion group) were enrolled in this study between December 2014-April 2021. The MRI and DCE-MRI data of the two groups of patients were collected and analyzed retrospectively. Results: Conventional MRI showed that the probabilities of irregular lesions, capsule wall>3.0mm, parenchyma>3.0mm, and massive pelvic effusion were greater in the ovarian tumor group than in the tumor-like lesion group (P<0.05). The largest diameter of the lesion in the ovarian tumor group was (12.30±3.68) cm, larger than (9.00±1.01) cm in the tumor-like lesion group (P<0.05). DCE-MRI showed that the volume transfer constant (Ktrans), extravascular extracellular volume fraction (Ve), and rate constant (Kep) of the region of interest (ROI) in the ovarian tumor group were greater than those in the tumor-like lesion group (P<0.05). The receiver operating characteristic (ROC) curve analysis showed that the sensitivity of MRI combined with DCE-MRI in differential diagnosis of ovarian tumors and tumor-like lesions was the highest, which was 93.83% (P<0.05). Youden index, area under the curve (AUC) and 95% CI were 0.757, 0.878, and 0.827 ~ 0.919. Conclusion: Both MRI and DCE-MRI have certain value in the diagnosis of ovarian tumors and tumor-like lesions, and the combination of the two has the highest value. Patients with ovarian tumors have more irregular lesions with thicker capsule walls, more parenchyma and larger diameters, more pelvic effusion, and larger Ktrans, Kep and Ve in DCE-MRI. In clinical practice, conventional MRI and functional MRI can be combined to differentiate benign and malignant ovarian lesions, thereby improving the accuracy and enable patients to receive treatment as soon as possible.
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2021, Vol. 27 
