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| An Experimental Research of the Effect of Self-drafting Woman's Blood Soup on Dysfunctional Uterine Bleeding on Rat Model |
| LI Zongguo, REN Chunyan, SU Xidong, et al |
| Chengde Hospital of Traditional Chinese Medicine, Hebei Chengde 067000, China |
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Abstract Objective: To study the effect of self-drafting woman's blood soup on dysfunctional uterine bleeding on rat model. Methods: A rat model of dysfunctional uterine bleeding was established. The rats were randomly divided into a model group, a positive control group, and low-dose and high-dose groups, with 10 rats in each group. Another ten pregnant rats were used as a blank group. On the first day after the successful modeling (ie, the 8th day of pregnancy), the low-dose and high-dose groups were respectively given 15--30 g/kg of the self-drafting woman's blood soup. The positive control group was intragastrically given self-drafting woman's blood soup for 0.07 g / kg. The blank group and the model group were intragastrically administered with the same dose of self-drafting woman's blood soup once a day for 7 days. The bleeding time and coagulation function, serum hormone levels and uterus and ovarian index of each group were measured. Results: Compared with the model group, the bleeding time, PT and TT of the positive control group and the low-dose and high-dose groups were significantly shortened, and the FIB was significantly increased (P<0.05). The bleeding time, PT and TT of the low- and high-dose groups were lower than those of the positive control group, and FIB was significantly higher than the positive control group, but there was no significant difference (P>0.05). Compared with the model group, the levels of serum E2, P, and FSH in the positive control group and the low-dose and high-dose groups were significantly decreased, and LH was significantly increased (P<0.05). The low and high dose groups and the positive control group can significantly increase the uterus and ovarian index of rats (P<0.01). Conclusion: The self-drafting woman's blood soup can improve the dysfunctional uterine bleeding of the rat model.
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2020, Vol. 26 
