中性粒细胞淋巴细胞比值对急性脑梗患者不良预后的预测价值

doi:10.3969/j.issn.1006-6233.2020.07.004

Abstract
Figure/Table
References
Related Citation (0)

Download: PDF (1264 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective: To explore the predictive value of peripheral blood neutrophil lymphocyte ratio (NLR) in the poor prognosis of patients with acute cerebral infarction. Methods: 660 patients with acute cerebral infarction (onset<72h) from January 2017 to May 2018 in the center for encephalopathy of Jiangsu Hospital of Chinese medicine were retrospectively included. The ability of NLR to predict the unfavorable prognosis of 90 days was tested by using the ROC curve, and the survival of patients was analyzed by Kaplan Meier survival curve. Results: NLR had a certain value in predicting the poor prognosis of patients with acute cerebral infarction. Kaplan Meier survival analysis showed that the survival rate of patients with NLR > 3.23 was significantly lower than that of patients with NRL ≤ 3.23 (log rank P = 0.000). Conclusion: The higher level of NLR has a certain predictive value for predicting the short-term survival of ACI patients in the early stage, and is related to the higher risk of death at 90 days.

Key words： Neutrophil-lymphocyte ratio Unfavorable prognosis

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	CAO Xiaofeng
	WU Minghua

Cite this article:

CAO Xiaofeng,WU Minghua. The Predictive Value of the Ratio of Neutrophils to Lymphocytes in Patients with Acute Cerebral Infarction[J]. HeBei Med, 2020, 26(7): 1072-1074.

URL:

http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2020.07.004 OR http://www.hbyxzzs.cn/EN/Y2020/V26/I7/1072

[1] S L, W S, H Z, et al. Microrna-145 accelerates the inflammatory reaction through activation of NF-κB signaling in atherosclerosis cells and mice [J]. Biomedicine & pharmacotherapy,2018,103(85):1~7.
[2] 中华医学会神经病学分会,中华医学会神经病学分会脑血管病学组.中国急性缺血性脑卒中诊治指南2014[J].中华神经科杂志,2015,48(4):246~257.
[3] X F, X Z, F Y, et al. Low-normal free triiodothyronine and high leukocyte levels in relation to stroke severity and poor outcome in acute ischemic stroke with intracranial atherosclerotic stenosis [J]. The International Journal of Neuroscience, 2019, 129(7): 635~641.
[4] MW M, J W, Q Z, et al. NADPH oxidase in brain injury and neurodegenerative disorders [J]. Molecular Neurodegeneration, 2017, 12(1): 7.
[5] Q S, Y L, Y W, et al. Increased neutrophil-to-lymphocyte ratios are associated with greater risk of hemorrhagic transformation in patients with acute ischemic stroke [J]. Current neurovascular research, 2018, 15(4): 326~335.
[6] AB P, RD E, KN S, et al. Temporal dynamics of peripheral neutrophil and lymphocytes following acute ischemic stroke [J]. Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2019, 40(9): 1877~1885.
[7] J G, SU B M, M M, et al. Stability across time of the neutrophil-lymphocyte and lymphocyte-neutrophil ratios and associations with outcomes in cardiac surgery patients [J]. Journal of Cardiothoracic Surgery, 2019, 14(1): 164.
[8] T C, S D M, E C, et al. Neutrophil-to-Lymphocyte Ratio is a strong predictor of atherosclerotic carotid plaques in older adults [J]. Nutrition Metabolism and Cardiovascular Diseases : NMCD, 2018, 28(1): 23~27.
[9] R Z, X W, W H, et al. Neutrophil-to-lymphocyte ratio predicts hemorrhagic transformation in ischemic stroke: A meta-analysis [J]. Brain and Behavior, 2019, 9(9): e01382.
[10] J Z, Q R, Y S, et al. Prognostic role of neutrophil-lymphocyte ratio in patients with acute ischemic stroke [J]. Medicine, 2017, 96(45): e8624.