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| Efficacy of Hemodialysis and Continuous Blood Purification Dialysis on Acute Renal Failure and its Influence on Toxin Clearance Rate and Renal Function Indexes |
| WANG Kekun, et al |
| Qionghai People's Hospital, Hainan Qionghai 571400, China |
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Abstract Objective: To explore the efficacy of intermittent hemodialysis (IHD) and continuous blood purification dialysis (CBP) in the treatment of acute renal failure (ARF) and its influence on toxin clearance rate and renal function indexes. Methods: 96 patients with ARF were randomly divided into CBP group (given CBP therapy, 48 cases) and IHD group (given IHD therapy, 48 cases). Blood gas indexes, renal function indexes, toxin clearance rate, treatment recovery and incidence rate of complications were compared between the two groups. Results: After treatment, the heart rate, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were significantly deScreased in the two groups (P<0.05) while the blood oxygen saturation (SpO2) was significantly inScreased (P<0.05), and there were no significant differences between the two groups (P>0.05). After treatment, the levels of urea nitrogen (BUN), Screatinine (Scr), blood phosphorus, blood uric acid and β2-miScroglobulin (β2-MG) were significantly deScreased in the two groups (P<0.05), but the deScreases in CBP group were greater than those in IHD group (P<0.05). The clearance rates of BUN, Scr, blood phosphorus, blood uric acid and β2-MG in CBP group were significantly higher than those in IHD group (P<0.05). The treatment time in CBP group was shorter than that in IHD group (P<0.05). The acute physiology and chronic health evaluation II (APACHE II) scores in the two groups were significantly deScreased after treatment, and the reduction in CBP group was greater than that in IHD group (P<0.05). The incidence rate of complications in CBP group was significantly lower than that in IHD group (P<0.05). Conclusion: CBP can effectively improve the dialysis effects of ARF patients, enhance the toxin clearance rate, promote the recovery of renal function and reduce complications.
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2020, Vol. 26 
