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| Clinical Effect of Carboprost Tromethamine on Postpartum Hemorrhage in High-risk Pregnancy |
| LIANG Hongyan |
| Hospital of Weichang Manchu Mongolian Autonomous County, Hebei Weichang 068450,China |
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Abstract Objective:To investigate the clinical effect of carboprost tromethamine in the treatment of postpartum hemorrhage in high-risk pregnancy. Methods:In this study, 50 high-risk pregnant women who delivered in the country hospital from March 2018 to September 2018 were selected as the research objects and divided into two groups with random number method (n=25).Both groups underwent cesarean section after combined spinal-epidural anesthesia. After the delivery, the control group received an intrauterine injection of 10U oxytocin and misoprostol tablets for anal plugging, while the observation group received an intrauterine injection of 10U oxytocin and another injection of 1ml carboprost tromethamine. Results:24 hours after delivery, the hemoglobin levels of the two groups were lower than those before delivery (P<0.05), and hemoglobin level of the observation group was higher than that of the control group (P<0.05). 24 hours after delivery, there was no significant difference in systolic and diastolic blood pressure between the two groups (P>0.05). The amount of bleeding during operation, 2 hours after delivery and 24 hours after delivery in the observation group was lower than that in the control group (P<0.05). Conclusions:Carboprost tromethamine can inhibit the decrease of hemoglobin level, which is conducive to reducing intraoperative and postpartum hemorrhage in high-risk pregnancies.
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2020, Vol. 26 
