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| Analysis on Correlation between Inflammatory Cytokines in Type 2 Diabetes Mellitus and Cardiovascular and Cerebrovascular Diseases |
| SHAN Hong, WU Yanxiang |
| Northern Theater Air Force Hospital, Liaoning Shenyang 110000, China |
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Abstract Objective: To investigate the correlation between inflammatory cytokines in type 2 diabetes and cardiovascular and cerebrovascular diseases. Methods: From January 2018 to April 2019, 114 patients with type 2 diabetes admitted to our hospital were divided into two groups: the non combined group and the combined group, with 57 cases in each group. In addition, 57 outpatients were selected as the healthy group, All the selected persons were examined by carotid ultrasound to understand the pathological changes, and the levels of TNF - α, C-reactive protein, soluble intercellular adhesion molecule-1, soluble vascular cell adhesion molecule-1 and monocyte chemoattractant protein were detected by blood sampling. The results were analyzed and summarized. Results: The carotid intima thickening, the formation of carotid atherosclerotic plaque and the detection rate of carotid stenosis in the healthy group, the non combined group and the combined group were all gradually increased (P<0.05). The levels of TNF - α, C-reactive protein, soluble intercellular adhesion molecule-1, soluble vascular cell adhesion molecule-1 and monocyte chemoattractant protein in the healthy group, the non combined group and the combined group were gradually increased, and the difference was statistically significant (P<0.05). Conclusion: There is a correlation between the levels of inflammatory factors and cardiovascular and cerebrovascular diseases in type 2 diabetes. Inflammatory factors are risk factors for cardiovascular and cerebrovascular diseases in patients with type 2 diabetes.
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[1] 文燕.2型糖尿病合并高血压患者心脑血管病变的相关危险因素分析[J].中国基层医药,2017,24(8):1243~1245.
[2] 温远平,罗爱国.家庭医生在社区2型糖尿病的健康管理及护理中的效果[J].哈尔滨医药,2017,36(6):551~552.
[3] 刘伟,陈贞,朱慧君,等.自拟养阴益气活血汤联合常规疗法治疗2型糖尿病下肢血管病变(气阴两虚兼血瘀证)的临床研究[J].中医药信息,2018,35(2):98~100.
[4] 马朝军.老年2型糖尿病合并心脑血管病变的危险因素探析[J].中国实用医药,2016,11(16):76~77.
[5] 陈比特.老年2型糖尿病合并高血压患者的心脑血管病变相关危险因素分析[J].黑龙江医药科学,2018,41(2):71~72.
[6] 王晓红.2型糖尿病患者血清脂联素及C反应蛋白与心脑血管病变的关系[J].中国医刊,2017,52(10):92~95. |
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2020, Vol. 26 
