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| Effect of PS Combined with Noninvasive Positive Pressure Ventilation on Neonatal Respiratory Distress and Blood Gas Index |
| CHEN Shaojun, CHEN Quanjing, ZHOU Fengxia |
| Dongfeng Hospital Affiliated to Hubei Medical College, Hubei Shiyan 442008, China |
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Abstract Objective: To study the effect of Lung surface active substances (PS) combined with noninvasive positive pressure ventilationin treatment of Neonatal respiratory distressand its effectson blood gas index. Methods: 100 newborn patients with respiratory distress admitted to our hospital from February 2017 to February 2019 were selected for the study,by stochastic indicator method, divided into the observation group (n = 52) and control group (n = 48) and control group using noninvasive positive pressure ventilation therapy, observation group on the basis of this combined therapy with PS, comparing two groups of clinical curative effect, the hydrogen ion concentration index (pH), CO2 partial pressure (PCO2), oxygenation index (PaO2 / FiO2) level, the aeration time level of complications, length of hospital stay, hospital expenses. Results: After treatment, the total effective rate of the observation group was 90.38% higher than that of the control group (P<0.05). Before treatment, there was no significant difference in blood gas index between the two groups (P>0.05). After treatment, blood gas index levels of children in both groups were significantly improved compared with those before treatment (P<0.05). PH, PaO2/FiO2 levels of children in the observation group were significantly higher than those in the control group, and PCO2 levels were significantly lower than those in the control group (P<0.05). Ventilation time, length of stay and cost of hospitalization in the observation group were significantly lower than those in the control group (P<0.05). The total incidence of adverse reactions in the two groups was 19.23% and 43.75%, respectively, with significant differences (P<0.05). Conclusion: PS combined with non-invasive positive pressure ventilation has a significant effect in the treatment of neonatal respiratory distress, which can effectively improve the blood gas index of children, and is worthy of promotion and application.
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2020, Vol. 26 
