|
|
The Effect of Orthodontic Micro Implant on MMP-2 MMP-9 and Bcl-2/Bax Level in Patients with Amis II Malocclusion |
YUAN Ying, WANG Lunchang |
Guangyuan Central Hospital, Sichuan Guangyuan 628000,China |
|
|
Abstract Objective: To analyze the effect of orthodontic micro-implant on MMP-2、MMP-9 and Bcl-2/Bax levels in patients with class II malocclusion. Methods: 110 patients admitted from January 2018 to December 2019 with class II malocclusion were randomly divided into observation group and control group. The control group had traditional orthodontic treatment, while the observation group had microimplant. The changes of MMP-2、MMP-9 and Bcl-2/Bax levels before and after treatment were observed, and the incidence of complications was different. Result: Repeated measurement analysis of variance showed that the differences of MMP-2 and MMP-9 between different groups and time points and the interaction between groups and time points were statistically significant (all P<0.05), and the increase of MMP-2 and MMP-9 in the control group was significantly higher than that in the observation group (P<0.05); the repeated measurement analysis of variance showed that the difference of Bcl-2/Bax value between different groups and time points, and the interaction between groups and time points were statistically significant (all P<0.05), and the Bcl-2/Bax value in the control group was significantly lower than that in the observation group (P<0.05). The incidence rates of complications during treatment in the observation group were 5.45% and 18.18%, and the difference between the two groups was statistically significant(P<0.05). Conclusion: The level of inflammatory factors caused by micro implants in orthodontic treatment of patients with class II malocclusion is lower than that of traditional orthodontic treatment, which is helpful to reduce the damage caused by orthodontic treatment to periodontal tissue, and the complications are less. So it is worth popularizing.
|
|
|
|
|
[1] 宋卫军,郑琳琳,李寒,等.安氏Ⅰ类和安氏Ⅱ类错牙合畸形正畸后上切牙牙根吸收的临床研究[J].临床口腔医学杂志,2019,35(3):166~169. [2] 胡芳,罗俊,田巍,等.口腔正畸改建术联合康复新液治疗错颌畸形患者的疗效及对龈沟液RANKL OPG的影响[J].河北医学,2017,23(10):1638~1642. [3] 吴可,谷妍,周明智,等.配合前牙种植支抗矫治安氏Ⅱ2错牙合畸形的疗效研究[J].口腔医学,2019,39(6):514~518. [4] 唐敏,陈妍曲,邹道星,等.高精度三维整合牙颌模型在计算机辅助设计与制作个体化微种植体手术导板中的应用研究[J].中华口腔正畸学杂志,2018,25(2):88~91. [5] 王婷,刘林,陈荟忆,等.微型种植体支抗在青年口腔正畸治疗中的应用效果分析[J].西南国防医药,2019,29(7):746~748. [6] 张丹丹,许晓虎.牙周炎大鼠MMP-2、BGP及炎性细胞因子的表达特点及低氧对于相关因子的影响[J].医学研究杂志,2018,47(6):176~179. [7] 范宗静,吴旸,唐杰,等.缺血再灌注损伤人心脏微血管内皮细胞凋亡基因Bcl-2、Bax的表达及黄芪多糖干预研究[J].中华中医药杂志,2017,32(12):5603~5606. [8] 史珂,张明珠,刘彦,等.增生性龈炎和牙龈瘤中bcl-2、bax基因表达的实验[J].昆明医科大学学报,2019,40(10):11~14. [9] 苗朝旭,王竞博,房博.正畸微型种植体对安氏Ⅱ类错颌畸形患者牙周炎症及MMP-2、MMP-9的影响[J].海南医学,2019,30(12):1578~1580. |
|
|
|