|
|
|
| Diagnostic Value of Chemical Staining Combined with Blue Laser Magnifying Endoscopy on Early Esophageal Carcinoma and Precancerous Lesions |
| HUA Haiyang, et al |
| Chengde Central Hospital, Hebei Chengde067000, China |
|
|
|
|
Abstract Objective: To investigate the value of chemical staining combined with blue laser magnifying endoscopy in the diagnosis of early esophageal carcinoma and precancerous lesions. Methods: From May 2017 to May 2019,100 patients with 138 suspicious esophageal lesions were examined by endoscopy in our hospital. The 100 patients were examined by blue laser magnifying endoscopy, iodine staining and blue laser magnifying endoscopy combined with iodine staining, and the pathological diagnosis was taken as the gold index. Kappa consistency test was performed for the microscopic and pathological results of the three methods, and the reliability of the McNemar chi-squartest was evaluated by sensitivity, specificity, positive predictive value, negative predictive value and Youden Index. Results: The combination of blue laser amplification and iodine staining showed good consistency, high sensitivity, specificity, positive predictive value, negative predictive value and Youden index. Conclusion: The combination of blue laser amplification and iodine staining can improve the diagnosis rate of early esophageal carcinoma.
|
|
|
|
|
|
[1] 李辉,游宾.中国食管外科临床研究的发展与前景[J].中华消化外科杂志,2018,17(1):14~17.
[2] 牟欢,吴清明.窄带成像内镜技术对食管癌的诊断研究[J].检验医学与临床,2018,15(12):1786~1788.
[3] 张勇,张铭,张文斌,等.NBI+放大联合碘染色对早期食管癌及癌前病变的诊断价值探讨[J].肿瘤学杂志,2014,20(4):320~322.
[4] 孙君军,李建华,李建辉,等.蓝激光成像及染色技术对消化道早癌诊断的研究现状[J].陕西医学杂志,2019,48(9):1243~1246.
[5] 易楠,农兵,张文华,等.内镜下蓝激光成像技术与碘染色诊断多原发食管癌的对比研究[J].中国临床新医学,2019,12(7):729~733.
[6] 李伊敏,程树红,张世豪.IPCL分类对食管早期肿瘤诊断价值的应用[J].蚌埠医学院学报,2019,44(6):742~744.
[7] Xiaofeng Duan,Weiwei Bai,Zhao Ma,et al. Management and outcomes of anastomotic leakage after McKeown esophagectomy: a retrospective analysis of 749 consecutive patients with esophageal cancer[J]. Surgical Oncology,2020,34:304~309.
[8] 邵丽华,张秋宁,田金徽,等.食管癌临床指南和共识的质量评价[J].中国循证医学杂志,2020,20(5):593~603.
[9] 孙君军,李建华,李建辉,等.化学染色结合蓝激光放大内镜对胃早期癌性病变的诊断价值[J].浙江医学,2020,42(8):806~810,887.
[10] Zhu Ying,Wang Fang,Zhou Yan,et al. Blue laser magnifying endoscopy in the diagnosis of chronic gastritis.[J]. Experimental and therapeutic medicine,2019,18(3):1993~2000.
[11] 高原,罗长琴,杨小翠.碘染色技术在食管癌高发区早癌诊断中的应用价值[J].山西医科大学学报,2018,49(8):949~951
[12] Mengfei Liu,Zhen Liu,Fangfang Liu,et al. Absence of iodine staining associates with progression of esophageal lesions in a prospective endoscopic surveillance study in China[J]. Clinical Gastroenterology and Hepatology,2020,18(7):1626~1635.
[13] 徐瑾,邱雁,赵君宁.窄带成像与卢戈氏碘染色诊断老年病人食管早癌及癌前病变的对比研究[J].实用老年医学,2018,32(12):1146~1149.
[14] 孙晴,潘恩春,孙中明,等.2009年至2017年淮安市食管癌高发地区内镜筛查结果分析[J].中华肿瘤防治杂志,2020,27(4):251~255. |
|
|
|
2020, Vol. 26 
