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| Clinical Observation of 5-FU Sustained-release Seeds Implantation Combined with Tegafur in the treatment of Digestive Tract Tumor |
| LIU Xianxing, LIANG Jingbo, CHANG Fan, et al |
| Third People's Hospital of Xining, Qinghai Xining 810005, China |
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Abstract Objective: To observe the curative effect of endoscopic implantation of slow-releasing 5-fluorour acil in combination with tegafur on gastrointestinal tumors. Methods: From March 2011 to March 2014, 70 patients with gastrointestinal tumors were treated in our hospital. These enrolled patients were simple randomly divided into observation group and control group according to the random principles, with 35 cases in each group. Both groups were treated with tegafur, and the observation group was treated with 5-fluorour acil on the basis of control group. The efficacy and survival quality of the two groups were compared after 3 months. Results: After 3 months' treatment, the observation group effective rate was higher (P<0.05). when survival quality efficiency rate and total efficiency rate were comapared, the observation group was higher than the control group respectively (P＜0.05). After 3 months of treatment, the fatigue status of the two groups was compared. The observation group was slightly less fatigued and had lower fatigue score than control group(P<0.05). Conclusion: Curative therapy of endoscopic implantation of slow-releasing 5-fluorour acil in combination with tegafur is effective and can improve the survival quality for patients with gastrointestinal tumors. Thus, it's well worth of being popularized.
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2020, Vol. 26 
