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| Analysis on Value of Multivoxel and Monovoxel of 1H-MRS in the Diagnosis of Low-grade Glioma Acute and Subacute Cerebral Infarction and Viral Encephalitis |
| BAI Xuedong, QIU Hengzhi, WANG Shenglin, et al |
| Affiliated Hospital of Chengde Medical College, Hebei Chengde 067000, China |
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Abstract Objective: To explore the value of H-MRS SVS and CSI in the diagnosis of low-grade gliomas, Acute and subacute cerebral infarction and viral encephalitis. Methods: The clinical and imaging data of 76 patients in our hospital were analyzed retrospectively, including 27 cases of viral encephalitis, 28 cases of cerebral infarction, 21 cases of low-grade gliomas. All patients were examined with magnetic Verio 3.0T MR for routine MR, SVS and CSI, and the spectral data were analyzed with spectroscopy software to compare the ratio of MRS metabolites in the three groups. Results: Cho / Cr, NAA / CHO, NAA / Cr in low-grade gliomas, viral encephalitis and cerebral infarction analysis of variance showed significant differences, further comparisons: There were significant differences in CHO / Cr, NAA / CHO, NAA / Cr between low-grade gliomas and encephalitis (P<0.05), Cho / Cr, NAA / CHO, NAA / CR of low-grade glioma were higher than those of encephalitis group and cerebral infarction group (P<0.05), There was no significant difference in NAA / CHO and NAA / Cr (P>0.05). Lac peak was found in 2 cases of low-grade gliomas, 18 cases of MI peak and 24 cases of cerebral infarction. When Cho / Cr diagnostic threshold was 2.35, the sensitivity and specificity of differentiating low-grade gliomas from viral encephalitis and cerebral infarction were 90.5% and 91% respectively. Conclusion: The combination of multivoxel and single voxel technology of 1 HMRS has certain clinical value in the differential diagnosis of low-grade glioma, acute and subacute cerebral infarction and viral encephalitis. Cho / Cr ratio is of great value in differentiating low-grade glioma from acute and subacute viral encephalitis and cerebral infarction.
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2020, Vol. 26 
