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| Effect of Wuling Capsule on Clinical Efficacy and Negative Emotion in Patients with Post-stroke Depression |
| WANG Shijun, LUAN Shuxin, WAN Hongquan, et al |
| The First Hospital of Jilin University, Jilin Changchun 130021, China |
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Abstract Objective: To investigate the effect of Wuling Capsule on the efficacy and safety of post-stroke depression patients. Methods: The subjects were 90 patients with post-stroke depression who were treated in our hospital from June 2017 to July 2018. They were simply randomly divided into treatment group (45 cases) and control group (45 cases). In the control group, patients with post-stroke depression were treated with western medicine fluoxetine, while in the treatment group, patients were treated with traditional Chinese medicine Wuling capsule. Through the treatment of two different schemes, the treatment effects of the control group and the treatment group were compared and analyzed. It mainly includes the improvement of clinical indicators and clinical treatment effect, the change of cytokines in patients after treatment and the adverse reactions of patients after treatment. Results: The HAMD score and Bi score of the treatment group were significantly higher than those of the control group (P < 0.05); the total effective rate of the treatment group was 91.67%, significantly higher than 70.00% of the control group (P < 0.05); the cytokine IL-6 and TNF - α of the treatment group were significantly lower than those of the control group (P < 0.05); compared with the control group, The rate of adverse reactions in the treatment group was significantly lower than that in the control group (P < 0.05). Conclusion: Wuling Capsule improves the clinical efficacy of patients with post-stroke depression. In terms of adverse reactions, Wuling Capsule also has a certain improvement effect.
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2020, Vol. 26 
