血清S-ChE LPO及血常规联合检测对老年重症肺炎预后的评估

doi:10.3969/j.issn.1006-6233.2019.09.013

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Abstract Objective: To study evaluation of prognosis of Severe Pneumonia by Serum S-ChE, LPO, Routine blood. Methods: 175 patients of severe pneumonia who received therapy from May 2016 and May 2018 in our hospital were selected, According to the condition of the disease, it was divided into 75 cases of delayed deterioration group and 100 cases of improvement group. Serum S-ChE, LPO and blood routine (WBC, PLT) levels of the two groups were detected. Results: Serum s-ChE and LPO levels in the worsening group were higher than the improving group (P<0.05), but there was no significant difference between the two groups (P<0.05). According to ROC curve analysis, the area under the ROC curve of s-ChE in evaluating the prognosis of severe pneumonia was 0.857, with sensitivity of 75.34%, specificity of 79.39%, accuracy rate of 78.29%, evaluation curve area of LPO was 0.772, sensitivity of 73.68%, specificity of 72.03% and accuracy of 72.57%. Blood routine evaluation curve area was 0.643, sensitivity 51.92%, specificity of 60.98% , accuracy 58.29%, and the combined prediction curve area was 0.913, sensitivity 81.58%, specificity 86.87% and accuracy 84.57%, all of which were higher than individual prediction, with significant difference (P<0.05). Conclusion: The prognosis of severe pneumonia in the elderly is related to changes in serum S-ChE and LPO levels of patients, and has no obvious relationship with blood routine. It is of great clinical significance to jointly evaluate the prognosis of severe pneumonia in the elderly.

Key words： Severe pneumonia S-ChE LPO

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	WU Taiping
	LIU Ling

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WU Taiping,LIU Ling. Evaluation of Prognosis of Severe Pneumonia by Serum S-ChE LPO Routine Blood[J]. HeBei Med, 2019, 25(9): 1459-1462.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2019.09.013 OR http://www.hbyxzzs.cn/EN/Y2019/V25/I9/1459

[1] Edibolu , Ataman S, Kirakli C. Characteristics of influenza pneumonia patients admitted to the ICU due to hypoxemic respiratory failure[J].Tuberk Toraks,2018,66(1):52~56.
[2] 刘杰,吴向玲,王园园,等.老年重症肺炎临床特点及诊治进展[J].实用老年医学,2018,32(10):13~16.
[3] 王立民,张建,戈艳蕾,等.老年重症肺炎患者预后的影响因素分析[J].山东医药,2017,57(12):65~67.
[4] 中华医学会呼吸病学分会.社区获得性肺炎诊断和治疗指南[J].中国实用乡村医生杂志,2013,20(2):158~160.
[5] Bartovska Z, Zlamal M, Murinova I, et al. A case of patient with AIDS and pneumocystis pneumonia complicated by cytomegalovirus pneumonitis[J]. Klin Mikrobiol Infekc Lek,2018,24(1):10~13.
[6] 沈丹,曹萍,李睿,等.联合检测早期血清胆碱酯酶和过氧化脂质水平对老年严重脓毒症患者预后的评估作用[J].广东医学,2017,38(6):925~927.
[7] 江蓉,刘建华,徐内卫.等.总胆汁酸、尿酸和胆碱酯酶检测在乙型肝炎肝硬化中的意义[J].国际检验医学杂志,2016,37(12):1724~1726.
[8] Cheabu S, Moung-Ngam P, Arikit S, et al. Effects of heat stress at vegetative and reproductive stages on spikelet fertility[J]. Rice Science,2018, 25(4):218~226.
[9] Mo X,Tang H,Zeng L, et al.The value of determination of serum cholinesterase levels in judgment of severity and prognosis in patients with severe pneumonia[J]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue,2016,28(1):38~43.
[10] 彭敏,闫超.瑞舒伐他汀钙对老年慢性心力衰竭患者氧化-抗氧化系统及血管内皮细胞功能的影响[J].新乡医学院学报,2017,34(8):751~754.
[11] 王冬梅,袁宝军,高利常,等.壹期矽肺患者血清中HO-1、LPO和IP-10含量变化[J].职业与健康,2016,32(13):1754~1756.
[12] Kolesnikova L I, Kolesnikov S I, Darenskaya M A, et al. Activity of LPO processes in women with polycystic ovarian syndrome and infertility[J]. Bulletin of Experimental Biology & Medicine, 2017, 162(3):1~3.
[13] 莫新,吴志刚,吴伟博,等.重症肺炎患者早期血清胆碱酯酶含量的变化及其相关性探讨[J].热带医学杂志,2017,17(6):723~726.
[14] 向娟,吴佳妮,唐兵.CD4~+CD25~+调节性T细胞及血小板参数在重症肺炎患者中表达的意义[J].标记免疫分析与临床,2016,23(11):1299~1302.