|
|
|
| Diagnostic Value of Conventional Ultrasound and Elastography with Fine Needle Aspiration Cytology in Thyroid Microcarcinoma |
| WU Wenying, WANG Xiaoyan, ZHAO Li, et al |
| The Affiliated Hospital of Chengde Medical College, Hebei Chengde 067000, China |
|
|
|
|
Abstract Objective: To investigate the diagnostic value of conventional ultrasound(CUS),ultrasound elastography(UE) and fine needle aspiration cytology(FNA) in thyroid microcarcinoma.Methods:279 thyroid nodules confirmed by operation and pathology were retrospectively analyzed. The diagnostic criteria of thyroid cancer were greater than or equal to 4 scores of elastic score and Bethesda report system classification ≥Ⅴ, and the diagnostic sensitivity, specificity, positive predictive value, negative predictive value and correct rate were calculated respectively compared with the pathological gold standard.Result:Of the 279 nodules, 124 were malignant and 155 were benign; 121 were malignant and 158 were benign by CUS, 170 were malignant and 109 were benign by UE, 162 were malignant and 117 were benign by FNA,102 were malignant and 177 were benign by CUS+UE series,106 were malignant and 173 were benign by CUS+FNA series. The sensitivity of UE and FNA for diagnosing thyroid microcarcinoma was higher than that of CUS, while specificity and positive predictive value were lower than CUS, and the difference was statistically significant(P<0.05).The CUS+UE series specificity, correct rate, positive predictive value and Eugene index were higher than CUS, the difference was statistically significant (P<0.05). The CUS+ FNA series specificity and positive predictive value were higher than CUS, the difference was statistically significant (P<0.05).Conclusion:CUS, UE and FNA have certain deficiencies in the diagnosis of thyroid microcarcinoma. CUS+ UE series and CUS+ FNA series specificity is higher than CUS, which can improve the early diagnosis of thyroid microcarcinoma and has high clinical value. At the same time, CUS+UE series is superior to CUS+FNA series in terms of non-invasiveness and low cost, which is worthy of clinical promotion.
|
|
|
|
|
|
[1] Remonti LR,Kramer CK,Leitao CB,et al. Thyroidultrasound features and risk of carcinoma:a systematic review andmeta -analysis of observational studies[J].Thyroid,2015,25 ( 5):538~550.
[2] 鄢曹鑫,罗志艳,刘学明,等.常规超声与超声弹性成像联合评分诊断甲状腺良恶性占位的探讨[J].中华医学杂志,2013,93(21):1630~1633.
[3] 邢媛媛,刘海芳,李亮,等.甲状腺乳头状癌超声特征及弹性成像分析[J].中国超声医学杂志,2017,33(6):484~487.
[4] Tian W,Hao S,Gao B,et al. Comparing the diagnostic accuracy of RTE and SWE in differentiating malignant thyroid nodules from benign ones:a Meta-Analysis[J].Cellular Physiology and Biochemistry,2016,39(6):2451~2463.
[5] 那子悦,乔强,王秋程,等.甲状腺剪切波弹性成像假性结果二维超声特点的分析[J].临床耳鼻咽喉头颈外科杂志,2017,30(15):1191~1195.
[6] 吴启敏,王超洋.146例甲状腺结节细胞穿刺病理学分析[J].中国中西医结合外科杂志,2015,21(1):70~71.
[7] 倪晓枫,詹继伟,宋琳琳,等.超声引导下细针穿刺抽吸活检诊断甲状腺结节[J].中国介入影像与治疗学,2013,10(8):461~464.
[8] 中华医学会内分泌学分会,中华医学会外科学分会,中国抗癌协会头颈肿瘤专业委员会,等.甲状腺结节和分化型甲状腺癌诊治指南[J].中国肿瘤临床,2012,39(17):1249~1272. |
|
|
|
2019, Vol. 25 
