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| Effect of Azithromycin combined with Tebutaline Inhalation on Inflammatory Factors and Immune Function in Children with Mycoplasmal Pneumonia |
| XIAO Yun, WANG Jiangang, ZHANG Di |
| Yingkou Central Hospital, Liaoning Yingkou 115002, China |
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Abstract Objective: To investigate the effects of azithromycin combined with teptoline inhalation on inflammatory factors and immune function in children with mycoplasmal pneumonia. Methods: A retrospective analysis of 70 children with mycoplasmal pneumonia admitted to our department from January 2015 to January 2018. All children were divided into two groups according to different treatment methods. 30 patients in the control group were given oral azithromycin tablets. treatment. Forty patients in the combined treatment group were given nebulized inhalation therapy with pedicalin on the basis of the control group. Both groups were treated for 7 days. Results: Before treatment, TNF-α was combined treatment group (70.35±3.62) pg/ml, control group (69.94±4.10) pg/ml; hs-CRP was combined treatment group (22.27±5.67) pg/ml, control Group (21.99±5.02) pg/ml, the difference was not statistically significant. After treatment, TNF-α and hs-CRP were significantly decreased in the two groups. TNF-α was (34.03±3.72) pg/ml in the combination group and (21.99±5.02) pg/ml in the control group; hs-CRP They were (8.32±2.17) pg/ml, (13.48±3.75) pg/ml, and difference is significant (P<0.05). There were no significant differences in the immunological function between the two groups before treatment (P>0.05). After treatment, IgA, IgG, C3, and C4 were significantly increased in the two groups, the difference is significant(P<0.05), and the combination treatment group was significantly better than the control group(P<0.05). The time of disappearance of fever, the time of disappearance of sputum, the time of disappearance of cough and the length of hospital stay were significantly shorter in the combined treatment group than in the control group, and the difference was not statistically(P<0.05). Conclusion: The use of azithromycin combined with teptoline inhalation in children with mycoplasmal pneumonia can better improve the inflammatory factor level and immune function of children, so that children can recover their body temperature, eliminate their voices and cure cough in a short time. Early sunrise, the effect is exact.
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2019, Vol. 25 
