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| Study on the Relationship between Serum IL-1β IL-6 IL-8 and the Pain of Patient with Acute Gouty Arthritis |
| LIANG Hui, ZHANG Yitong, XIE Jihui, et al |
| Shijiazhuang Traditional Chinese Medicine Hospital, Hebei Shijiazhuang 050051, China |
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Abstract Objective: To study the relationship between the expression of serum IL-1β,IL-6 and IL-8 and pain in patients with acute gouty arthritis(AGA). Methods: 60 patients with AGA in Shijiazhuang Hospital of Traditional Chinese Medicine from March 2017 to June 2018 were selected as observation group, 30 healthy persons at the same time were selected as control group, then serum IL-1β,IL-6 and IL-8 of two groups were detected and compared, and the detection levels of observation group with different pain index were compared, then the relationship between serum IL-1β,IL-6 and IL-8 and the pain degree of patients were analyzed by Pearson correlation analysis. Results: The serum IL-1β,IL-6 and IL-8 of observation group were all significantly higher than those of control group, and there was a positive correlation between the degree of pain and the level of serum IL-1β,IL-6,IL-8 in observation group by Pearson correlation analysis, the difference was statistically significant(P<0.05). Conclusions: Serum IL-1β,IL-6 and IL-8 was positively correlated with pain in patients with acute gouty arthritis, and had high clinical value in acute gouty arthritis.
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2019, Vol. 25 
