|
|
|
| Clinical Observation on Wuzi Mingmu Recipe Combined with Acupuncture and Moxibustion Therapy in the Treatment of Retinitis pigmentosa |
| ZHOU Xianlin, KONG Lin |
| Suizhou Hospital Affiliated to Hubei Medical College, Hubei Suizhou 441300, China |
|
|
|
|
Abstract Objective: To investigate the clinical effects of Wuzi Mingmu recipe combined with acupuncture and moxibustion in the treatment of retinitis pigmentosa (RP). Methods: 54 cases of RP patients (108 eyes) treated between June 2015 and June 2017 were divided into the treatment group and the control group by random number table method, each with 27 cases (54 eyes). The two groups were given western medicine, and the treatment group was given Wuzi Mingmu recipe combined with acupuncture and moxibustion on this basis. The clinical efficacy was compared in the two groups, and the visual field (mean light sensitivity, mean defect), hemorheology (whole blood viscosity, plasma viscosity, fibrinogen, erythrocyte aggregation index) and electroretinogram b wave (latency time, amplitude) were evaluated before treatment and after 8w of treatment. Results: After 8w of treatment, the clinical efficacy in the treatment group was better than that in the control group (P<0.05). After 8w of treatment, the mean light sensitivity of the two groups was significantly higher than that before treatment (P<0.05) while the mean defect was lower than that before treatment (P<0.05), and the change degree in the treatment group was higher that in the control group (P<0.05). After 8w of treatment, the hemorheology indexes (whole blood viscosity, plasma viscosity, fibrinogen, erythrocyte aggregation index), and the b wave latency times of dark adaptation and light adaptation in the treatment group were lower than those before treatment (P<0.05) and those in the control group at the same period (P<0.05) while the b wave amplitudes of dark adaptation and light adaptation were higher than those before treatment and in the control group at the same period (P<0.05), and there was no statistical significance in the levels of hemorheology indexes and the amplitude and latency time of b wave in the control group before and after treatment (P>0.05). Conclusions: Wuzi Mingmu recipe combined with acupuncture and moxibustion can have good efficacy in the treatment of RP, and it is beneficial to improve the visual acuity and visual field of patients.
|
|
|
|
|
|
[1] 李淑贤,刘铁城,陈晓菲,等.视网膜色素变性的基因治疗进展[J].解放军医学院学报,2017,38(1):82~84.
[2] 张延菊,方晓丽.温通针法治疗原发性视网膜色素变性的临床观察[J].中国中医眼科杂志,2015,25(4):259~262.
[3] 郭梦翔,闫利锋,周瑾,等.原发性视网膜色素变性患者血清脂蛋白与血流参数相关性研究[J].临床眼科杂志,2017,25(2):97~99.
[4] 葛坚,赵家.眼科学[M].北京:人民卫生出版社,2005.317.
[5] 曾庆华.中医眼科学[M],北京:人民卫生出版社,2003.213.
[6] 刘昳,张元钟,章青.银杏明目方治疗原发性视网膜色素变性[J].长春中医药大学学报,2017,33(1):115~117.
[7] 钱天威,许迅.视网膜色素变性治疗策略的研究进展[J].中华眼科杂志,2017,53(2):148~153.
[8] 董胜利.中医固肾益血疗法治疗色素变性30例[J].世界中医药,2016,11(b03):1227~1228.
[9] 杜青,冯乐,王方.视网膜色素变性疾病的OCT表现[J].眼科新进展,2016,36(4):374~376.
[10] 王磊,张磊,王亚娜,等.补肾丸合明目五子治疗干眼症的临床疗效[J].国际眼科杂志,2017,17(8):1593~1595.
[11] 包力,王晓悦,杜采凤,等.原发性视网膜色素变性患者全视野视网膜电图及光学相干断层扫描分析[J].华西医学,2016,31(11):1818~1821. |
|
|
|
2018, Vol. 24 
