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| Clinical Application on Acute Non-normalvolemic Hemodilution in Laparoscopic Hepatectomy |
| ZHANG Yuenong, DENG Jingdan, LUO Rong, et al |
| Meizhou People's Hospital, Guangdong Meizhou 514000, China |
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Abstract Objective: To investigate the safety and effectiveness of the acute non-normalvolemic hemodilution (ANIH) method in laparoscopic hepatectomy. Method: 50 patients were selected for laparoscopic hepatectomy. According to the treatment method, it was divided into the ANIH group and the control group, with the age ranging from 21 to 77 years. The two groups were all operated with low central venous pressure under control, and the number of intraoperative blood loss and allogeneic blood transfusion cases in the two groups were compared. The postoperative hospitalization time, mean arterial pressure, heart rate and liver function before and after surgery were compared. Results: There was no significant difference in the level of CVP, HR and MAP before operation (P > 0.05) in the two groups. The level of CVP and the level of MAP after blood collection in group ANIH were lower than those in the control group (P < 0.05), and there was no significant difference between the two groups at each period of the HR level (P > 0.05). The liver function related indexes of group ANIH and control group before and after operation (AST, ALT, ALB, TBIL), there was no significant difference between the two groups before operation (P>0.05). The liver function indexes were improved after the operation, and the difference was statistically significant (P < 0.05) before and after operation (P < 0.05). The liver function index of ANIH group was improved compared with the control group. The situation was better. The bleeding volume in group ANIH was lower than that in the control group (P < 0.05), and there was no significant difference in the number of allogeneic blood samples (P>0.05). The recovery time of gastrointestinal tract in group ANIH was significantly lower than that in control group (P < 0.05), and there was no significant difference in hospitalization time between the two groups (P>0.05). Conclusion: The application of acute non-isovolemic hemodilution in laparoscopic hepatectomy is helpful to control low central venous pressure, reduce the chance of bleeding and transfusion of allogeneic blood, and is safe and reliable for patients during perioperative period.
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2018, Vol. 24 
