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| Diagnostic Value of Non-enhanced MRI and Diffusion Weighted Imaging in Adult Prostate Cancer: a Meta analysis |
| CHEN Song, ZHAO Mingzeng, YANG Ruwu, et al |
| Xidian Group Hospital, Shanxi Xi'an 710077, China |
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Abstract Objective: To evaluate the overall diagnostic value of non-enhanced MRI and DWI in adults with Prostate cancer. Methods: All the papers concerning the diagnosis of prostate cancer using non-enhanced MRI and DWI in both English and Chinese published had been searched and reviewed, and the studies with the surgery or pathology as the gold standard were adopted as eligible. According to the requirements of Meta analysis and the recognized quality standard of diagnostic test, we assessed whether all the included studies were eligible and extracted the characteristic information of the above studies.Stata14.0 software was used to test the heterogeneity of the above features. After that, MetaDisc1.4 software was used to calculate the total sensitivity and specificity. The diagnostic accuracy of the method was evaluated by Meta, and the receiver operating characteristic curve (SROC) was used to evaluate the accuracy of the method. Results: 16 articles were in accordance with the inclusion criteria. The pooled indexes of diagnostic performance and summary receiver operating characteristic curve (SROC) demonstrated a high discriminatory power for detection prostate cancer by non-enhanced MRI and DWI. In the pooled estimates, sensitivity and specificity were 59%(95% confidence interval 0.57 to 0.61) and 89 %(95% confidence interval 0.88 to 0.90) respectively, AUC was 0.879 . Conclusion: Non-enhanced MRI and DWI may be a highly accurate and non-invasion diagnostic tool for detecting prostate cancer in dults.
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2018, Vol. 24 
