叶酸联合阿托伐他汀对H型高血压患者颈总动脉内膜中层厚度的影响

doi:10.3969/j.issn.1006-6233.2018.06.019

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Abstract Objective: To study the effect of folic acid combined with atorvastatin on carotid artery intima-media thickness in patients with Hypertension. Methods: A total of 144 H-type hypertensive patients admitted to our hospital from January 2016 to July 2017 were enrolled in this study. All patients underwent no antihypertensive drugs in the recent 1 month and were randomly divided into observation group and control group. Group folic acid combined with atorvastatin treatment, the control group was treated with atorvastatin, 6 months follow-up, Hcy levels in patients with bilateral carotid artery IMT were measured. Results: After treatment, the systolic blood pressure (138.71±6.93mmHg vs 141.77±10.24mmHg) and diastolic blood pressure (90.82±7.12mmHg vs 94.72±6.55mmHg) were significantly different between the two groups (P<0.05), and the observation group was at the level of Hcy ( 9.82±3.11umol/L vs 12.32±3.18umol/L) and IMT (1.14±0.11mm vs 1.29±0.15mm) were significantly better than the control group, P<0.05, and the difference was statistically significant. Conclusion: Folic acid combined with atorvastatin has significant clinical efficacy in reducing Hcy level and decreasing IMT thickness of common carotid artery in patients with H type hypertension, which is worthy of clinical promotion.

Key words： Folic acid Atorvastatin Hypertension Common carotid artery Intima-media thickness

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	BAI Yan

Cite this article:

BAI Yan. Effect of Folic Acid Combined with Atorvastatin on Carotid Artery Intima-media Thickness in Patients with Type H Hypertension[J]. HeBei Med, 2018, 24(6): 955-957.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2018.06.019 OR http://www.hbyxzzs.cn/EN/Y2018/V24/I6/955