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| Effect of Perioperative Fast Track Surgery (FTS) on Postoperative Inflammatory Stress Reaction and Prognosis in Patients with Colorectal Cancer and Diabetes Mellitus |
| HE Fang, BIAN Yajin, CHANG Weiwei |
| The Second Hospital of Qinhuangdao, Hebei Qinhuangdao 066600, China |
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Abstract Objective: To investigate the effect of perioperative fast track surgery (FTS) on postoperative inflammatory stress reaction and prognosis in patients with colorectal cancer and diabetes mellitus. Methods: According to the random number table method,eighty patients with colorectal cancer and diabetes mellitus were divided into two groups:the control group(D group)and the observation group (F group).The patients in the control group were performed with routine perioperative treatment,while the patients in the observation group were given FTS perioperative treatment.Prognosis and the difference of postoperative inflammatory stress reaction between the two groups were observed.Results: Therewere no significant differences in age and duration of diabetes between the two groups(P<0.05).The defecation time,anal exhaust time,wound healing time and hospitalization time in group F were significantly shorter than those in group D (P<0.05).At the same time,the weight,hemoglobin and albumin reduction of group F were significantly lower than those in group D (P<0.05);The incidence of postoperative complications in group F (7.50%) was significantly lower than that in group D (32.50%) (P<0.05),and the level of inflammation index (CRP,IL-6,SAA,TNF- a) in group F was significantly better than that in group Dat postoperative 5 days (P<0.05). Conclusion: It is of great significance to reduce the incidence of complications,control the level of inflammation,shorten the time of rehabilitation and improve the prognosis by using the FTS concept for the perioperative management of colorectal carcinomacomplicated with diabetes mellitus.
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2018, Vol. 24 
