子痫前期孕妇TG TC LDL-C LDL-C/HDL-C的特征及与不良妊娠结局关系的研究

doi:10.3969/j.issn.1006-6233.2018.10.030

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Abstract Objective:To analyze the characteristics of TG, TC, LDL-C, LDL-C/HDL-C in preeclampsia and its relationship with adverse pregnancy outcomes. Methods:A total of 98 cases of preeclampsia pregnant women were selected, the 98 cases healthy pregnant women of the hospital in the same period were randomly selected as the control group. The lipid levels of the two groups were measured, including total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and calculated blood lipid ratio TC/HDL-C, TG/HDL-C, LDL-C/HDL-C and were compared between the PE group and the control group. The pregnancy outcome of pregnant women with PE was observed, compare TC, TG, LDL-C, HDL-C, TC/HDL-C, TG/HDL-C, LDL-C/HDL-C in pregnant women with adverse pregnancy outcomes and those without adverse pregnancy outcomes. And analyzed multivariate logistic regression analysis of adverse pregnancy outcomes. Results: There were no significant difference in serum TC, LDL-C and HDL-C between the two groups (P>0.05). The serum TG levels in PE group was significantly higher than that in control group (t=6.556, P<0.05). The TC/HDL-C, TG/HDL-C, and LDL-C/HDL-C in the PE group were significantly higher than those in the control group (t=4.723, 7.996, 5.445, P<0.05). Among 98 pregnant women with PE, the overall incidence of adverse pregnancy outcomes was 24.48% (24/98). There were no significant difference in the levels of TC, LDL-C and HDL-C between pregnant women with adverse pregnancy outcomes and those without adverse pregnancy outcomes (P>0.05), while the TG、TC/HDL-C、TG/HDL-C、LDL-C/HDL-C levels were statistically significant (P<0.05). The multivariate logistic regression analysis showed that TC/HDL-C, TG/HDL-C, and LDL-C/HDL-C were the influencing factors of adverse pregnancy outcome (P<0.05). Conclusion: The TG, TC/HDL-C, TG/HDL-C, and LDL-C/HDL-C in PE pregnant women were significantly higher than those in the control group, among which TC/HDL-C, TG/HDL-C, LDL-C/HDL-C Influencing factors for adverse pregnancy outcomes in PE pregnant women.

Key words： Preeclampsia Blood lipid levels Blood lipid ratio Pregnancy outcomes Relevance

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	LIANG Qin
	ZHOU La

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LIANG Qin,ZHOU La. Characteristics of TG, TC, LDL-C, LDL-C/HDL-C in Preeclampsiaand the Relationship with Adverse Pregnancy Outcomes[J]. HeBei Med, 2018, 24(10): 1707-1710.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2018.10.030 OR http://www.hbyxzzs.cn/EN/Y2018/V24/I10/1707

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