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| Determination of Protein C in Serum and Cerebrospinal Fluidin Children with Viral Encephalitis and Clinical Research |
| WANG Yan |
| The Affiliated Hospital of Chengde Medical College, Hebei Chengde 067000, China |
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Abstract Objective: To study the changes of protein C levelsin serum and cerebrospinal fluid(CSF) of children with viral encephalitis and its clinical significance. Method:From October 2013 to December 2015,102 cases of children with viral encephalitis as the observation group, the other in the same period randomly selected 100 cases of children with upper respiratory tract infection with headache as control group.In hospital within 24 h (acute phase) and the clinical therapy (recovery) after 1 weeks to collect children venous blood samples and cerebrospinal fluid samples for detection of protein C levels;collecting and the detecting protein C levels of healthy children in the venous blood samples and samples of cerebrospinal fluid. Results: Observation group with acute phase protein C levels in serum and cerebrospinal fluid were relatively lower than recovery children and healthy children, the differences were statistically significant (P<0.05).Observation group children with acute mild protein C levels in serum and cerebrospinal fluid were higher than children with severe, differences were statistically significant (t=2.542, 2.115, P<0.05). Conclusion: Protein C levels can be used for the early diagnosis of viral encephalitis and judge the severity of infection, having important clinical value for diagnosis and treatmentof children with viral encephalitis.
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2017, Vol. 23 
