腹腔镜手术对胆囊结石合并急性胆囊炎患者机体应激及免疫功能的影响

doi:10.3969/j.issn.1006-6233.2017.09.010

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Abstract Objective: To investigate the effects of laparoscopic surgery on the stress and immune function of patients with cholecystolithiasis complicated with acute cholecystitis. Methods: 60 patients with cholecystolithiasis combined with acute cholecystitis from May 2014 to May 2017 were randomly divided into two groups. Laparoscopic group patients underwent laparoscopic surgery. The patients in the traditional group were given traditional surgery. The related clinical indicators, complications, stress levels, immune function and quality of life were compared. Results: The incision scar length, length of hospital stay and total complication rate in laparoscopic group were significantly lower than those in the traditional group. The levels of IL-6, CRP, cortisol, ACTH and blood glucose were significantly lower than those of the traditional group (P <0.05). There was significant difference between the two groups (P <0.05). The difference of CD3, CD4 and CD4/CD8 levels between the two groups was significantly higher than that of the conventional group (P <0.01). Conclusion: Laparoscopic surgery has a significant effect on the body's stress and immune function in patients with gallstone and acute cholecystitis.

Key words： Laparoscopic surgery Gallstones Acute cholecystitis Body stress Immune function

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LI Jin. Effects of Laparoscopic Surgery on Stress and Immune Function in Patients with Gallstones Complicated with Acute Cholecystitis[J]. 河北医学, 2017, 23(9): 1440-1443.

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http://www.hbyxzzs.cn/EN/10.3969/j.issn.1006-6233.2017.09.010 OR http://www.hbyxzzs.cn/EN/Y2017/V23/I9/1440

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