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Predictive Value of New Injury Severity Score in Stress Ulcer of Shock Patients with Multiple Trauma |
LUO Xiaomin, et al |
Renmin Hospital of Wuhan University, Hubei Wuhan 430060, China |
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Abstract Objective: To explore the predictive value of new injury severity score (NISS) in stress ulcer of shock patients with multiple trauma. Methods: Clinical data of 92 ICU shock patients suffered from multiple trauma were retrospectively reviewed between August 2015 and September 2016. The patients were divided into two groups with either stress ulcer present (20 cases) or absent (72 cases). Some clinical characteristics were compared between two groups. Multivariate logistic regression and receiver operating characteristic curve (ROC) were performed to identify independent risk factors of stress ulcer and the predictive accuracy. Results: The difference in shock degree and mechanical ventilation were statistically significant between two groups (P<0.05), while that in gender, age, ratio of glucocorticoid usage or operative treatment between two groups didn't reach significant level (P>0.05). The scores of NISS, ISS and APACHE Ⅱ were obviously higher in the stress ulcer group than non-stress ulcer group (29.00±5.26 vs.23.32±4.04, 26.25±5.48 vs.21.72±3.74 and 18.10±4.29 vs.15.42±3.73, respectively, P<0.05 for all). Multivariate logistic regression analysis showed that only NISS was correlated with the incidence of stress ulcer. The area under the cure for NISS was 0.825 by ROC analysis. The best boundary value of NISS was 26.5 with the sensitivity, specificity, positive predictive and negative predictive values of 85.0%, 77.8%, 51.5% and 94.9%, respectively. Conclusions: NISS is an independent risk factor for stress ulcer in shock patients suffered from multiple trauma. NISS can predict stress ulcer with a good accuracy in this population.
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